Linked Life Data

20731799

Source:http://linkedlifedata.com/resource/pubmed/id/20731799

Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:20731799rdf:typepubmed:Citationlld:pubmed
pubmed-article:20731799lifeskim:mentionsumls-concept:C0043250lld:lifeskim
pubmed-article:20731799lifeskim:mentionsumls-concept:C0034693lld:lifeskim
pubmed-article:20731799lifeskim:mentionsumls-concept:C0043240lld:lifeskim
pubmed-article:20731799lifeskim:mentionsumls-concept:C0002475lld:lifeskim
pubmed-article:20731799lifeskim:mentionsumls-concept:C0008141lld:lifeskim
pubmed-article:20731799lifeskim:mentionsumls-concept:C0162969lld:lifeskim
pubmed-article:20731799lifeskim:mentionsumls-concept:C0102137lld:lifeskim
pubmed-article:20731799lifeskim:mentionsumls-concept:C0460765lld:lifeskim
pubmed-article:20731799lifeskim:mentionsumls-concept:C2349975lld:lifeskim
pubmed-article:20731799lifeskim:mentionsumls-concept:C0060794lld:lifeskim
pubmed-article:20731799pubmed:issue5lld:pubmed
pubmed-article:20731799pubmed:dateCreated2010-9-15lld:pubmed
pubmed-article:20731799pubmed:abstractTextTo create a moist environment for rapid wound healing, a hydrosheet composed of alginate, chitin/chitosan, and fucoidan (ACF-HS) has been developed as a functional wound dressing. The aim of this study was to evaluate the accelerating effect of ACF-HS on wound healing for rat mitomycin C-treated healing-impaired wounds. Full-thickness skin defects were made on the back of rats and mitomycin C was applied onto the wound for 10 minutes to prepare a healing-impaired wound. After thoroughly washing out the mitomycin C, ACF-HS was applied to the healing-impaired wounds. The rats were later euthanized and histological sections of the wounds were prepared. The histological examinations showed significantly advanced granulation tissue and capillary formations in the healing-impaired wounds treated with ACF-HS on days 7 and 14, in comparison with that in alginate fiber (Kaltostat), hydrogel wound dressing (DuoACTIVE), and nontreatment (negative control). Furthermore, in cell culture studies, ACF-HS-absorbed serum and fibroblast growth factor-2 was found to be proliferative for fibroblasts and endothelial cells, respectively, and ACF-HS-absorbed serum was found to be chemoattractive for fibroblasts. However, our results may not be strictly comparable with general healing-impaired wound models in humans because of the cell damage by mitomycin C. In addition, more biocompatibility studies of fucoidan are essential due to the possibility of renal toxicity.lld:pubmed
pubmed-article:20731799pubmed:languageenglld:pubmed
pubmed-article:20731799pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:20731799pubmed:citationSubsetIMlld:pubmed
pubmed-article:20731799pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:20731799pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:20731799pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:20731799pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:20731799pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:20731799pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:20731799pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:20731799pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:20731799pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:20731799pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:20731799pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:20731799pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:20731799pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:20731799pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:20731799pubmed:statusMEDLINElld:pubmed
pubmed-article:20731799pubmed:issn1524-475Xlld:pubmed
pubmed-article:20731799pubmed:authorpubmed-author:IshiharaMasay...lld:pubmed
pubmed-article:20731799pubmed:authorpubmed-author:YokoeHidetaka...lld:pubmed
pubmed-article:20731799pubmed:authorpubmed-author:AokiHiroshiHlld:pubmed
pubmed-article:20731799pubmed:authorpubmed-author:SatoYasunoriYlld:pubmed
pubmed-article:20731799pubmed:authorpubmed-author:KiyosawaTomoh...lld:pubmed
pubmed-article:20731799pubmed:authorpubmed-author:MurakamiKaoru...lld:pubmed
pubmed-article:20731799pubmed:authorpubmed-author:NakamuraShing...lld:pubmed
pubmed-article:20731799pubmed:authorpubmed-author:NakamuraShin-...lld:pubmed
pubmed-article:20731799pubmed:authorpubmed-author:Yanagibayashi...lld:pubmed
pubmed-article:20731799pubmed:authorpubmed-author:KishimotoSato...lld:pubmed
pubmed-article:20731799pubmed:authorpubmed-author:TakikawaMegum...lld:pubmed
pubmed-article:20731799pubmed:copyrightInfo© 2010 by the Wound Healing Society.lld:pubmed
pubmed-article:20731799pubmed:issnTypeElectroniclld:pubmed
pubmed-article:20731799pubmed:volume18lld:pubmed
pubmed-article:20731799pubmed:ownerNLMlld:pubmed
pubmed-article:20731799pubmed:authorsCompleteYlld:pubmed
pubmed-article:20731799pubmed:pagination478-85lld:pubmed
pubmed-article:20731799pubmed:meshHeadingpubmed-meshheading:20731799...lld:pubmed
pubmed-article:20731799pubmed:meshHeadingpubmed-meshheading:20731799...lld:pubmed
pubmed-article:20731799pubmed:meshHeadingpubmed-meshheading:20731799...lld:pubmed
pubmed-article:20731799pubmed:meshHeadingpubmed-meshheading:20731799...lld:pubmed
pubmed-article:20731799pubmed:meshHeadingpubmed-meshheading:20731799...lld:pubmed
pubmed-article:20731799pubmed:meshHeadingpubmed-meshheading:20731799...lld:pubmed
pubmed-article:20731799pubmed:meshHeadingpubmed-meshheading:20731799...lld:pubmed
pubmed-article:20731799pubmed:meshHeadingpubmed-meshheading:20731799...lld:pubmed
pubmed-article:20731799pubmed:meshHeadingpubmed-meshheading:20731799...lld:pubmed
pubmed-article:20731799pubmed:meshHeadingpubmed-meshheading:20731799...lld:pubmed
pubmed-article:20731799pubmed:meshHeadingpubmed-meshheading:20731799...lld:pubmed
pubmed-article:20731799pubmed:meshHeadingpubmed-meshheading:20731799...lld:pubmed
pubmed-article:20731799pubmed:meshHeadingpubmed-meshheading:20731799...lld:pubmed
pubmed-article:20731799pubmed:meshHeadingpubmed-meshheading:20731799...lld:pubmed
pubmed-article:20731799pubmed:meshHeadingpubmed-meshheading:20731799...lld:pubmed
pubmed-article:20731799pubmed:meshHeadingpubmed-meshheading:20731799...lld:pubmed
pubmed-article:20731799pubmed:meshHeadingpubmed-meshheading:20731799...lld:pubmed
pubmed-article:20731799pubmed:meshHeadingpubmed-meshheading:20731799...lld:pubmed
pubmed-article:20731799pubmed:meshHeadingpubmed-meshheading:20731799...lld:pubmed
pubmed-article:20731799pubmed:meshHeadingpubmed-meshheading:20731799...lld:pubmed
pubmed-article:20731799pubmed:meshHeadingpubmed-meshheading:20731799...lld:pubmed
pubmed-article:20731799pubmed:meshHeadingpubmed-meshheading:20731799...lld:pubmed
pubmed-article:20731799pubmed:meshHeadingpubmed-meshheading:20731799...lld:pubmed
pubmed-article:20731799pubmed:meshHeadingpubmed-meshheading:20731799...lld:pubmed
pubmed-article:20731799pubmed:meshHeadingpubmed-meshheading:20731799...lld:pubmed
pubmed-article:20731799pubmed:meshHeadingpubmed-meshheading:20731799...lld:pubmed
pubmed-article:20731799pubmed:articleTitleEnhanced healing of mitomycin C-treated healing-impaired wounds in rats with hydrosheets composed of chitin/chitosan, fucoidan, and alginate as wound dressings.lld:pubmed
pubmed-article:20731799pubmed:affiliationDepartment of Oral and Maxillofacial Surgery Research Institute, National Defense Medical College, Tokorozawa, Saitama, Japan. dr22056@ndmc.ac.jplld:pubmed
pubmed-article:20731799pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:20731799pubmed:publicationTypeComparative Studylld:pubmed
pubmed-article:20731799pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed