Linked Life Data

20730382

Source:http://linkedlifedata.com/resource/pubmed/id/20730382

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2010-8-23
pubmed:abstractText
Fasciculation and elongation protein zeta-1 (FEZ1) is a mammalian ortholog of the Caenorhabditis elegans UNC-76 protein that possesses four coiled-coil domains and a nuclear localization signal. It is mainly expressed in the brain. Suppression of FEZ1 expression in cultured embryonic neurons causes deficiency of neuronal differentiation. Recently, proteomic techniques revealed that FEZ1 interacts with various intracellular partners, such as signaling, motor, and structural proteins. FEZ1 was shown to act as an antiviral factor. The findings reported so far indicate that FEZ1 is associated with neuronal development, neuropathologies, and viral infection. Based on these accumulating evidences, we herein review the biological functions of FEZ1.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1537-744X
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1646-54
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Functions of fasciculation and elongation protein zeta-1 (FEZ1) in the brain.
pubmed:affiliation
Department of Bioengineering, Nagaoka University of Technology, Niigata, Japan. maturana@vos.nagaokaut.ac.jp
pubmed:publicationType
Journal Article, Review