Linked Life Data

20729080

Source:http://linkedlifedata.com/resource/pubmed/id/20729080

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
19
pubmed:dateCreated
2010-9-13
pubmed:abstractText
We screened 1434 small heterocyclic molecules and identified thirteen 2,3,6-trisubstituted quinoxaline derivatives that were able to inhibit the Wnt/?-catenin signal pathway and cell proliferation. In the screen, some of the hit compounds such as the ethylene group-coupled quinoxaline derivatives were shown to hold promise for use as potential small-molecule inhibitors of the Wnt/?-catenin signal pathway in non-small-cell lung cancer cell lines.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1464-3405
pubmed:author
pubmed:copyrightInfo
Copyright © 2010 Elsevier Ltd. All rights reserved.
pubmed:issnType
Electronic
pubmed:day
1
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
5900-4
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Identification of 2,3,6-trisubstituted quinoxaline derivatives as a Wnt2/?-catenin pathway inhibitor in non-small-cell lung cancer cell lines.
pubmed:affiliation
Graduate School of Biotechnology, Korea University, Seoul 136701, Republic of Korea.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't