Source:http://linkedlifedata.com/resource/pubmed/id/20728839
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2010-8-23
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pubmed:abstractText |
Photodynamic therapy (PDT) has been used for pre-malignant mucosal lesions. In an attempt to treat a patient with recurrent high-grade dysplasia of the glottic larynx, we were faced with technical challenges leading us to abandon the classic microlens fiber for a 2-cm long translucent diffusing balloon catheter to deliver photoactivating light to the targeted lesion. Real-time measurements confirmed stable photobleaching with augmentation of the prescribed light fluence secondary to light scatter in regions not in contact with the balloon diffuser. We report a potential new application of the balloon catheter that may be more suitable for anterior glottic lesions associated with minimal acute toxicity.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1873-1597
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pubmed:author | |
pubmed:copyrightInfo |
(c) 2010 Elsevier B.V. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
158-61
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pubmed:meshHeading |
pubmed-meshheading:20728839-Aged,
pubmed-meshheading:20728839-Aminolevulinic Acid,
pubmed-meshheading:20728839-Balloon Dilation,
pubmed-meshheading:20728839-Esophagoscopes,
pubmed-meshheading:20728839-Glottis,
pubmed-meshheading:20728839-Humans,
pubmed-meshheading:20728839-Laryngeal Diseases,
pubmed-meshheading:20728839-Male,
pubmed-meshheading:20728839-Photochemotherapy,
pubmed-meshheading:20728839-Photosensitizing Agents
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pubmed:year |
2010
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pubmed:articleTitle |
Targeted laryngeal photodynamic therapy with a balloon diffusing light source.
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pubmed:affiliation |
Department of Radiation Oncology, University of Pennsylvania, PA, USA.
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pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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