Linked Life Data

20728197

Source:http://linkedlifedata.com/resource/pubmed/id/20728197

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
20
pubmed:dateCreated
2010-11-24
pubmed:abstractText
Municipal biosolids are in widespread use as additives to agricultural soils in the United States. Although it is well known that digested sewage sludge is laden with organic wastewater contaminants, the fate and behavior of micropollutants in biosolids-amended agricultural soils remain unclear. An outdoor mesocosm study was conducted in Baltimore, Maryland, to explore the fate of 72 pharmaceuticals and personal care products (PPCPs) over the course of three years in that were placed in plastic containers made from polyvinylchloride and kept exposed to ambient outdoor conditions. Of the 72 PPCPs tested for using EPA Method 1694, 15 were initially detected in the soil/biosolids mixtures at concentrations ranging from low parts-per-billion to parts-per-million levels. The antimicrobials triclocarban and triclosan showed the highest initial concentrations at 2715 and 1265 ?g kg(-1), respectively. Compounds showing no discernable loss over three years of monitoring included diphenhydramine, fluoxetine, thiabendazole and triclocarban. The following half-life estimates were obtained for compounds showing first-order loss rates: azithromycin (408-990 d) carbamazepine (462-533 d), ciprofloxacin (1155-3466 d), doxycycline (533-578 d), 4-epitetracycline (630 d), gemfibrozil (224-231 d), norfloxacin (990-1386 d), tetracycline (578 d), and triclosan (182-193 d). Consistent with other outdoor degradation studies, chemical half-lives determined empirically exceeded those reported from laboratory studies or predicted from fate models. Study results suggest that PPCPs shown in the laboratory to be readily biotransformable can persist in soils for extended periods of time when applied in biosolids. This study provides the first experimental data on the persistence in biosolids-amended soils for ciprofloxacin, diphenhydramine, doxycycline, 4-epitetracycline, gemfibrozil, miconazole, norfloxacin, ofloxacin, and thiabendazole.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Antimitotic Agents, http://linkedlifedata.com/resource/pubmed/chemical/Azithromycin, http://linkedlifedata.com/resource/pubmed/chemical/Carbamazepine, http://linkedlifedata.com/resource/pubmed/chemical/Carbanilides, http://linkedlifedata.com/resource/pubmed/chemical/Ciprofloxacin, http://linkedlifedata.com/resource/pubmed/chemical/Diphenhydramine, http://linkedlifedata.com/resource/pubmed/chemical/Doxycycline, http://linkedlifedata.com/resource/pubmed/chemical/Fluoxetine, http://linkedlifedata.com/resource/pubmed/chemical/Sewage, http://linkedlifedata.com/resource/pubmed/chemical/Soil, http://linkedlifedata.com/resource/pubmed/chemical/Tetracycline, http://linkedlifedata.com/resource/pubmed/chemical/Thiabendazole, http://linkedlifedata.com/resource/pubmed/chemical/Triclosan, http://linkedlifedata.com/resource/pubmed/chemical/triclocarban
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1879-2448
pubmed:author
pubmed:copyrightInfo
Copyright © 2010 Elsevier Ltd. All rights reserved.
pubmed:issnType
Electronic
pubmed:volume
44
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
6011-20
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Occurrence and loss over three years of 72 pharmaceuticals and personal care products from biosolids-soil mixtures in outdoor mesocosms.
pubmed:affiliation
Center for Environmental Biotechnology, The Biodesign Institute at Arizona State University, 1001 S. McAllister Avenue, Tempe, AZ 85287-5701, United States.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural