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rdf:type |
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|
lifeskim:mentions |
|
|
pubmed:issue |
18
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pubmed:dateCreated |
2010-9-10
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pubmed:abstractText |
A facile synthesis of chiral bicyclic amidines and imidazolines from readily available 1,2-diamines has been developed. The reported synthetic strategy relies on an intramolecular cyclization which involves a carboxylic amide derived imidoyl chloride as a key intermediate and aniline serving as a leaving group.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1523-7052
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pubmed:author |
|
|
pubmed:issnType |
Electronic
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pubmed:day |
17
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4156-9
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pubmed:meshHeading |
|
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pubmed:year |
2010
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pubmed:articleTitle |
Facile synthesis of bicyclic amidines and imidazolines from 1,2-diamines.
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|
pubmed:affiliation |
Department of Chemistry and Medicinal Chemistry Program, Life Sciences Institute, National University of Singapore, Singapore, Republic of Singapore.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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