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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2010-10-21
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pubmed:abstractText |
We present two cases of ciliated muconodular papillary tumour (CMPT) in this report. CMPT is a newly defined low-grade malignant tumour with ciliated columnar epithelial cells, occurring in the peripheral lung. Both patients underwent pulmonary resection due to an enlarged solitary pulmonary nodule. Pathological findings in both cases confirmed a papillary tumour with a mixture of ciliated columnar and goblet cells. The tumours were rich in mucous and had spread along the alveolar walls, as observed in bronchioloalveolar carcinoma. Nuclear atypia was mild, and no mitotic activity was observed. Immunohistochemically, tumour cells stained positive for carcinoembryonic antigen, thyroid transcription factor-1 and cytokeratin 7 but not for cytokeratin 20. The immunohistochemical staining patterns were almost identical to those of pulmonary adenocarcinoma. We definitively diagnosed as CMPT. Both patients remained relapse-free.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1569-9285
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
685-7
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pubmed:meshHeading |
pubmed-meshheading:20724424-Aged,
pubmed-meshheading:20724424-Carcinoembryonic Antigen,
pubmed-meshheading:20724424-Cilia,
pubmed-meshheading:20724424-Epithelial Cells,
pubmed-meshheading:20724424-Female,
pubmed-meshheading:20724424-Goblet Cells,
pubmed-meshheading:20724424-Humans,
pubmed-meshheading:20724424-Immunohistochemistry,
pubmed-meshheading:20724424-Keratin-7,
pubmed-meshheading:20724424-Lung Neoplasms,
pubmed-meshheading:20724424-Male,
pubmed-meshheading:20724424-Middle Aged,
pubmed-meshheading:20724424-Nuclear Proteins,
pubmed-meshheading:20724424-Pneumonectomy,
pubmed-meshheading:20724424-Solitary Pulmonary Nodule,
pubmed-meshheading:20724424-Terminology as Topic,
pubmed-meshheading:20724424-Tomography, X-Ray Computed,
pubmed-meshheading:20724424-Transcription Factors,
pubmed-meshheading:20724424-Treatment Outcome,
pubmed-meshheading:20724424-Tumor Markers, Biological
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pubmed:year |
2010
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pubmed:articleTitle |
Ciliated muconodular papillary tumour of the lung: a newly defined low-grade malignant tumour.
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pubmed:affiliation |
Division of Chest Surgery, Niigata Cancer Center Hospital, 2-15-3 Kawagishi-cho, Niigata 951-8566, Japan.
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pubmed:publicationType |
Journal Article,
Case Reports
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