|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
4
|
|
pubmed:dateCreated |
2011-3-10
|
|
pubmed:abstractText |
The organic cation transporter OCTN2 is located on the IBD5 risk allele and has been implicated in the pathogenesis of inflammatory bowel diseases (IBD). OCTN2 is expressed in the apical membrane and transports many solutes including bacteria-derived mediators that may be involved in host-microbial interactions. To explore its role further, we examined potential regulatory factors in human IBD and in experimental models of OCTN2 expression.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Cytokines,
http://linkedlifedata.com/resource/pubmed/chemical/Homeodomain Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Organic Cation Transport Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/RAG-1 protein,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Small Interfering,
http://linkedlifedata.com/resource/pubmed/chemical/SLC22A5 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Slc22a5 protein, mouse
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Apr
|
|
pubmed:issn |
1536-4844
|
|
pubmed:author |
|
|
pubmed:copyrightInfo |
Copyright © 2010 Crohn's & Crohn's & Colitis Foundation of America, Inc.
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
17
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
907-16
|
|
pubmed:meshHeading |
pubmed-meshheading:20722056-Animals,
pubmed-meshheading:20722056-Blotting, Western,
pubmed-meshheading:20722056-Cells, Cultured,
pubmed-meshheading:20722056-Colon,
pubmed-meshheading:20722056-Crohn Disease,
pubmed-meshheading:20722056-Cytokines,
pubmed-meshheading:20722056-Epithelial Cells,
pubmed-meshheading:20722056-Homeodomain Proteins,
pubmed-meshheading:20722056-Humans,
pubmed-meshheading:20722056-Immunoenzyme Techniques,
pubmed-meshheading:20722056-Intestine, Large,
pubmed-meshheading:20722056-Intestine, Small,
pubmed-meshheading:20722056-Mice,
pubmed-meshheading:20722056-Mice, Inbred C57BL,
pubmed-meshheading:20722056-Organic Cation Transport Proteins,
pubmed-meshheading:20722056-RNA, Messenger,
pubmed-meshheading:20722056-RNA, Small Interfering,
pubmed-meshheading:20722056-Reverse Transcriptase Polymerase Chain Reaction
|
|
pubmed:year |
2011
|
|
pubmed:articleTitle |
Cytokine regulation of OCTN2 expression and activity in small and large intestine.
|
|
pubmed:affiliation |
Department of Gastroenterology, Asahikawa Medical School, Asahikawa, Japan.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
|
