Source:http://linkedlifedata.com/resource/pubmed/id/20721529
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
|
pubmed:dateCreated |
2010-10-11
|
pubmed:abstractText |
Acute lung injury is characterized by an exaggerated inflammatory response and a high metabolic demand. Mechanical ventilation can contribute to lung injury, resulting in ventilator-induced lung injury (VILI). A suspended-animation-like state induced by hydrogen sulfide (H?S) protects against hypoxia-induced organ injury. We hypothesized that suspended animation is protective in VILI by reducing metabolism and thereby CO? production, allowing for a lower respiratory rate while maintaining adequate gas exchange. Alternatively, H?S may reduce inflammation in VILI.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
1432-1238
|
pubmed:author | |
pubmed:issnType |
Electronic
|
pubmed:volume |
36
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1946-52
|
pubmed:meshHeading |
pubmed-meshheading:20721529-Administration, Inhalation,
pubmed-meshheading:20721529-Animals,
pubmed-meshheading:20721529-Hydrogen Sulfide,
pubmed-meshheading:20721529-Inflammation,
pubmed-meshheading:20721529-Male,
pubmed-meshheading:20721529-Metabolism,
pubmed-meshheading:20721529-Monitoring, Physiologic,
pubmed-meshheading:20721529-Rats,
pubmed-meshheading:20721529-Rats, Sprague-Dawley,
pubmed-meshheading:20721529-Ventilator-Induced Lung Injury
|
pubmed:year |
2010
|
pubmed:articleTitle |
Suspended animation inducer hydrogen sulfide is protective in an in vivo model of ventilator-induced lung injury.
|
pubmed:affiliation |
Laboratory of Experimental Intensive Care and Anesthesiology (L.E.I.C.A.), Academic Medical Center, Amsterdam, The Netherlands.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|