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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2010-8-19
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pubmed:abstractText |
Proliferation of vascular smooth muscle cells (VSMCs) is a crucial event in the pathogenesis of intimal hyperplasia, the main cause of restenosis following vascular reconstruction. Here, the impact of sonic hedgehog (Shh)/Gli family zinc finger 2 (Gli2) signaling on VSMC proliferation was assessed.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Cyclin D1,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclin E,
http://linkedlifedata.com/resource/pubmed/chemical/Gli2 protein,
http://linkedlifedata.com/resource/pubmed/chemical/Hedgehog Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Kruppel-Like Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Fusion Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Retinoblastoma Protein,
http://linkedlifedata.com/resource/pubmed/chemical/SHH protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Shh protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Veratrum Alkaloids,
http://linkedlifedata.com/resource/pubmed/chemical/cyclopamine
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1524-4636
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
30
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1787-94
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pubmed:meshHeading |
pubmed-meshheading:20720195-Animals,
pubmed-meshheading:20720195-Cell Proliferation,
pubmed-meshheading:20720195-Cells, Cultured,
pubmed-meshheading:20720195-Cyclin D1,
pubmed-meshheading:20720195-Cyclin E,
pubmed-meshheading:20720195-Disease Models, Animal,
pubmed-meshheading:20720195-G1 Phase,
pubmed-meshheading:20720195-Graft Occlusion, Vascular,
pubmed-meshheading:20720195-Hedgehog Proteins,
pubmed-meshheading:20720195-Humans,
pubmed-meshheading:20720195-Hyperplasia,
pubmed-meshheading:20720195-Jugular Veins,
pubmed-meshheading:20720195-Kruppel-Like Transcription Factors,
pubmed-meshheading:20720195-Mice,
pubmed-meshheading:20720195-Mice, Inbred C57BL,
pubmed-meshheading:20720195-Muscle, Smooth, Vascular,
pubmed-meshheading:20720195-Phosphorylation,
pubmed-meshheading:20720195-RNA Interference,
pubmed-meshheading:20720195-Recombinant Fusion Proteins,
pubmed-meshheading:20720195-Retinoblastoma Protein,
pubmed-meshheading:20720195-S Phase,
pubmed-meshheading:20720195-Saphenous Vein,
pubmed-meshheading:20720195-Signal Transduction,
pubmed-meshheading:20720195-Veratrum Alkaloids
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pubmed:year |
2010
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pubmed:articleTitle |
Sonic hedgehog signaling induces vascular smooth muscle cell proliferation via induction of the G1 cyclin-retinoblastoma axis.
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pubmed:affiliation |
Department of Vascular Surgery, 1st Hospital of China Medical University, Shenyang, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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