|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0012314,
umls-concept:C0017431,
umls-concept:C0018684,
umls-concept:C0030705,
umls-concept:C0205099,
umls-concept:C0205372,
umls-concept:C0320385,
umls-concept:C1514811,
umls-concept:C1561577,
umls-concept:C1706462,
umls-concept:C1947933,
umls-concept:C2603343
|
|
pubmed:issue |
2
|
|
pubmed:dateCreated |
2011-1-17
|
|
pubmed:abstractText |
Studies on Pneumocystis jirovecii dihydropteroate synthase (DHPS) genotypes among non-HIV immunocompromised patients from developing countries are rare. In the present prospective investigation, 24 (11.8%) cases were found to be positive for Pneumocystis jirovecii out of 203 non-HIV patients with a clinical suspicion of Pneumocystis pneumonia (PCP). Dihydropteroate synthase (DHPS) genotype 1 (Thr55+Pro57) was noted in 95.8% P. jirovecii isolates in the present study in contrast to only 4.1% of patients with DHPS genotype 4 (Thr55Ala + Pro57Ser).
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Feb
|
|
pubmed:issn |
1460-2709
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
49
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
167-71
|
|
pubmed:meshHeading |
pubmed-meshheading:20718608-Adolescent,
pubmed-meshheading:20718608-Adult,
pubmed-meshheading:20718608-Amino Acid Substitution,
pubmed-meshheading:20718608-Child,
pubmed-meshheading:20718608-Child, Preschool,
pubmed-meshheading:20718608-Dihydropteroate Synthase,
pubmed-meshheading:20718608-Female,
pubmed-meshheading:20718608-Genotype,
pubmed-meshheading:20718608-Hospitals,
pubmed-meshheading:20718608-Humans,
pubmed-meshheading:20718608-Immunocompromised Host,
pubmed-meshheading:20718608-Infant,
pubmed-meshheading:20718608-Male,
pubmed-meshheading:20718608-Middle Aged,
pubmed-meshheading:20718608-Pneumocystis jirovecii,
pubmed-meshheading:20718608-Pneumonia, Pneumocystis,
pubmed-meshheading:20718608-Prospective Studies,
pubmed-meshheading:20718608-Young Adult
|
|
pubmed:year |
2011
|
|
pubmed:articleTitle |
Pneumocystis jirovecii dihydropteroate synthase (DHPS) genotypes in non-HIV-immunocompromised patients: a tertiary care reference health centre study.
|
|
pubmed:affiliation |
Department of Microbiology, All India Institute of Medical Sciences (AIIMS), New Delhi, India.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
