| pubmed-article:20718421 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:20718421 | lifeskim:mentions | umls-concept:C0011923 | lld:lifeskim |
| pubmed-article:20718421 | lifeskim:mentions | umls-concept:C0006118 | lld:lifeskim |
| pubmed-article:20718421 | lifeskim:mentions | umls-concept:C0001128 | lld:lifeskim |
| pubmed-article:20718421 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
| pubmed-article:20718421 | lifeskim:mentions | umls-concept:C0220825 | lld:lifeskim |
| pubmed-article:20718421 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
| pubmed-article:20718421 | lifeskim:mentions | umls-concept:C0032743 | lld:lifeskim |
| pubmed-article:20718421 | lifeskim:mentions | umls-concept:C0205460 | lld:lifeskim |
| pubmed-article:20718421 | pubmed:issue | 18 | lld:pubmed |
| pubmed-article:20718421 | pubmed:dateCreated | 2010-9-16 | lld:pubmed |
| pubmed-article:20718421 | pubmed:abstractText | (R,S)-anti-1-amino-2-fluorocyclopentyl-1-carboxylic acid (2-FACPC, 4b) was radiolabeled in 39% yield starting from cyclic sulfamidate 12. The 9L gliosarcoma cells assays showed that 4b is mainly a substrate for the L-type amino acid transport with some affinity to the A-type. In rats bearing 9L gliosarcoma tumors, 4b displayed high tumor to brain ratio (10:1) at 120 min after injection. FACPC is an attractive candidate for imaging brain tumors with PET, and its isolated enantiomers are under investigation. | lld:pubmed |
| pubmed-article:20718421 | pubmed:language | eng | lld:pubmed |
| pubmed-article:20718421 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20718421 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:20718421 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20718421 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20718421 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20718421 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20718421 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:20718421 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:20718421 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:20718421 | pubmed:issn | 1520-4804 | lld:pubmed |
| pubmed-article:20718421 | pubmed:author | pubmed-author:GoodmanMark... | lld:pubmed |
| pubmed-article:20718421 | pubmed:author | pubmed-author:CampVernon... | lld:pubmed |
| pubmed-article:20718421 | pubmed:author | pubmed-author:VollRonald... | lld:pubmed |
| pubmed-article:20718421 | pubmed:author | pubmed-author:WilliamsLarry... | lld:pubmed |
| pubmed-article:20718421 | pubmed:author | pubmed-author:JarkasNachwaN | lld:pubmed |
| pubmed-article:20718421 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:20718421 | pubmed:day | 23 | lld:pubmed |
| pubmed-article:20718421 | pubmed:volume | 53 | lld:pubmed |
| pubmed-article:20718421 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:20718421 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:20718421 | pubmed:pagination | 6603-7 | lld:pubmed |
| pubmed-article:20718421 | pubmed:meshHeading | pubmed-meshheading:20718421... | lld:pubmed |
| pubmed-article:20718421 | pubmed:meshHeading | pubmed-meshheading:20718421... | lld:pubmed |
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| pubmed-article:20718421 | pubmed:meshHeading | pubmed-meshheading:20718421... | lld:pubmed |
| pubmed-article:20718421 | pubmed:meshHeading | pubmed-meshheading:20718421... | lld:pubmed |
| pubmed-article:20718421 | pubmed:meshHeading | pubmed-meshheading:20718421... | lld:pubmed |
| pubmed-article:20718421 | pubmed:meshHeading | pubmed-meshheading:20718421... | lld:pubmed |
| pubmed-article:20718421 | pubmed:meshHeading | pubmed-meshheading:20718421... | lld:pubmed |
| pubmed-article:20718421 | pubmed:meshHeading | pubmed-meshheading:20718421... | lld:pubmed |
| pubmed-article:20718421 | pubmed:meshHeading | pubmed-meshheading:20718421... | lld:pubmed |
| pubmed-article:20718421 | pubmed:meshHeading | pubmed-meshheading:20718421... | lld:pubmed |
| pubmed-article:20718421 | pubmed:meshHeading | pubmed-meshheading:20718421... | lld:pubmed |
| pubmed-article:20718421 | pubmed:meshHeading | pubmed-meshheading:20718421... | lld:pubmed |
| pubmed-article:20718421 | pubmed:meshHeading | pubmed-meshheading:20718421... | lld:pubmed |
| pubmed-article:20718421 | pubmed:meshHeading | pubmed-meshheading:20718421... | lld:pubmed |
| pubmed-article:20718421 | pubmed:year | 2010 | lld:pubmed |
| pubmed-article:20718421 | pubmed:articleTitle | (R,S)-anti-1-amino-2-[18F]fluorocyclopentyl-1-carboxylic acid: synthesis from racemic 2-benzyloxycyclopentanone and biological evaluation for brain tumor imaging with positron emission tomography. | lld:pubmed |
| pubmed-article:20718421 | pubmed:affiliation | Department of Radiology, Emory University CSI, Wesley Woods Health Center, 1841 Clifton Road, NE, Atlanta, Georgia 30329, USA. | lld:pubmed |
| pubmed-article:20718421 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:20718421 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:20718421 | lld:chembl |
