Linked Life Data

20717951

Source:http://linkedlifedata.com/resource/pubmed/id/20717951

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
2010-8-30
pubmed:abstractText
The symptoms of allergic rhinitis result from an immunoglobulin E-dependent mast cell activation cascade, marked by the release of inflammatory mediators, including histamine. Patients with perennial allergic rhinitis also have elevated levels of cysteinyl leukotrienes (CysLTs) in nasal lavage fluid. Histamine and CysLTs produce different responses in the pathogenesis of allergic rhinitis, and this study tested the hypothesis that the effects of combined antihistamine and leukotriene antagonist therapy would be more effective than antihistamine alone.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1531-4995
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
120
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1718-23
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Efficacy of leukotriene antagonists as concomitant therapy in allergic rhinitis.
pubmed:affiliation
Department of Otorhinolaryngology and Head-Neck Surgery, Osmangazi University, Eskisehir, Turkey.
pubmed:publicationType
Journal Article, Comparative Study, Randomized Controlled Trial, Multicenter Study