Source:http://linkedlifedata.com/resource/pubmed/id/20715765
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
|
pubmed:dateCreated |
2010-9-24
|
pubmed:abstractText |
A new benzoquinone-type retro-dihydrochalcone, named evelynin, was isolated from the roots and rhizomes of Tacca chantrieri. The structure was elucidated on the basis of the analysis of spectroscopic data and confirmed by a simple one-step total synthesis. Evelynin exhibited cytotoxicity against four human cancer cell lines, MDA-MB-435 melanoma, MDA-MB-231 breast, PC-3 prostate, and HeLa cervical carcinoma cells, with IC(50) values of 4.1, 3.9, 4.7, and 6.3 ?M, respectively.
|
pubmed:grant | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
1520-6025
|
pubmed:author | |
pubmed:issnType |
Electronic
|
pubmed:day |
24
|
pubmed:volume |
73
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1590-2
|
pubmed:dateRevised |
2011-9-30
|
pubmed:meshHeading |
pubmed-meshheading:20715765-Antineoplastic Agents, Phytogenic,
pubmed-meshheading:20715765-Benzoquinones,
pubmed-meshheading:20715765-Chalcones,
pubmed-meshheading:20715765-Dioscoreaceae,
pubmed-meshheading:20715765-Drug Screening Assays, Antitumor,
pubmed-meshheading:20715765-Female,
pubmed-meshheading:20715765-HeLa Cells,
pubmed-meshheading:20715765-Humans,
pubmed-meshheading:20715765-Inhibitory Concentration 50,
pubmed-meshheading:20715765-Male,
pubmed-meshheading:20715765-Rhizome
|
pubmed:year |
2010
|
pubmed:articleTitle |
Evelynin, a cytotoxic benzoquinone-type Retro-dihydrochalcone from Tacca chantrieri.
|
pubmed:affiliation |
Department of Pharmacology and Cancer Therapy & Research Center, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229, USA.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, N.I.H., Extramural
|