Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
35
pubmed:dateCreated
2010-8-25
pubmed:abstractText
ESI mass spectrometry was used to assess the binding of 13-substituted, 5-nitro-2-phenylindolyl- and 2-naphthalenyl-based berberine derivatives to inter- and intramolecular G-quadruplex DNA molecules. In contrast with the parent berberine, the compounds showed selectivity for quadruplex over duplex DNA and stabilised the quadruplex structure. They represent a new class of quadruplex DNA-selective ligands.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1364-548X
pubmed:author
pubmed:issnType
Electronic
pubmed:day
21
pubmed:volume
46
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
6602-4
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
A mass spectrometric investigation of novel quadruplex DNA-selective berberine derivatives.
pubmed:affiliation
School of Chemistry, University of Wollongong, Wollongong, NSW 2522, Australia.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't