Source:http://linkedlifedata.com/resource/pubmed/id/20714562
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
35
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pubmed:dateCreated |
2010-8-25
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pubmed:abstractText |
ESI mass spectrometry was used to assess the binding of 13-substituted, 5-nitro-2-phenylindolyl- and 2-naphthalenyl-based berberine derivatives to inter- and intramolecular G-quadruplex DNA molecules. In contrast with the parent berberine, the compounds showed selectivity for quadruplex over duplex DNA and stabilised the quadruplex structure. They represent a new class of quadruplex DNA-selective ligands.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1364-548X
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:day |
21
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pubmed:volume |
46
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
6602-4
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pubmed:meshHeading | |
pubmed:year |
2010
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pubmed:articleTitle |
A mass spectrometric investigation of novel quadruplex DNA-selective berberine derivatives.
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pubmed:affiliation |
School of Chemistry, University of Wollongong, Wollongong, NSW 2522, Australia.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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