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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2010-10-4
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pubmed:abstractText |
Friedreich's ataxia (FRDA) and ataxia with oculomotor apraxia type 2 (AOA2) are the two most frequent forms of autosomal recessive cerebellar ataxias. However, brain metabolism in these disorders is poorly characterized and biomarkers of the disease progression are lacking. We aimed at assessing the neurochemical profile of the pons, the cerebellar hemisphere and the vermis in patients with FRDA and AOA2 to identify potential biomarkers of these diseases.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1872-6240
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pubmed:author |
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pubmed:copyrightInfo |
Published by Elsevier B.V.
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pubmed:issnType |
Electronic
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pubmed:day |
28
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pubmed:volume |
1358
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
200-10
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pubmed:dateRevised |
2011-10-28
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pubmed:meshHeading |
pubmed-meshheading:20713024-Adult,
pubmed-meshheading:20713024-Aspartic Acid,
pubmed-meshheading:20713024-Brain Mapping,
pubmed-meshheading:20713024-Creatine,
pubmed-meshheading:20713024-Female,
pubmed-meshheading:20713024-Friedreich Ataxia,
pubmed-meshheading:20713024-Gait Ataxia,
pubmed-meshheading:20713024-Glutamic Acid,
pubmed-meshheading:20713024-Humans,
pubmed-meshheading:20713024-Inositol,
pubmed-meshheading:20713024-Magnetic Resonance Imaging,
pubmed-meshheading:20713024-Magnetic Resonance Spectroscopy,
pubmed-meshheading:20713024-Male,
pubmed-meshheading:20713024-Middle Aged,
pubmed-meshheading:20713024-Ocular Motility Disorders,
pubmed-meshheading:20713024-Protons,
pubmed-meshheading:20713024-Spectrum Analysis,
pubmed-meshheading:20713024-Statistics as Topic,
pubmed-meshheading:20713024-Young Adult
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pubmed:year |
2010
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pubmed:articleTitle |
(1)H MR spectroscopy in Friedreich's ataxia and ataxia with oculomotor apraxia type 2.
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pubmed:affiliation |
Center for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, MN 55455, USA. isabelle@cmrr.umn.edu
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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