rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2010-10-18
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pubmed:abstractText |
The potent vasoconstrictor endothelin-1 has been implicated in the pathogenesis of the microcirculatory dysfunction seen in sepsis. The mixed endothelin receptor antagonist tezosentan and the selective endothelin A-receptor antagonist TBC3711 were used to investigate the importance of the different endothelin receptors in modulating splanchnic regional blood flow and microvascular blood flow in endotoxaemia.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Endothelin-1,
http://linkedlifedata.com/resource/pubmed/chemical/Isoxazoles,
http://linkedlifedata.com/resource/pubmed/chemical/N-(2-acetyl-4,6-dimethylphenyl)-3-(3...,
http://linkedlifedata.com/resource/pubmed/chemical/Pyridines,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Endothelin A,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Endothelin B,
http://linkedlifedata.com/resource/pubmed/chemical/Sulfones,
http://linkedlifedata.com/resource/pubmed/chemical/Tetrazoles,
http://linkedlifedata.com/resource/pubmed/chemical/Vasodilator Agents,
http://linkedlifedata.com/resource/pubmed/chemical/tezosentan
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1471-6771
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pubmed:author |
|
pubmed:issnType |
Electronic
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pubmed:volume |
105
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
640-7
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pubmed:meshHeading |
pubmed-meshheading:20710019-Animals,
pubmed-meshheading:20710019-Endothelin-1,
pubmed-meshheading:20710019-Endotoxemia,
pubmed-meshheading:20710019-Female,
pubmed-meshheading:20710019-Hypertension, Pulmonary,
pubmed-meshheading:20710019-Ileum,
pubmed-meshheading:20710019-Intestinal Mucosa,
pubmed-meshheading:20710019-Isoxazoles,
pubmed-meshheading:20710019-Microcirculation,
pubmed-meshheading:20710019-Pyridines,
pubmed-meshheading:20710019-Receptor, Endothelin A,
pubmed-meshheading:20710019-Receptor, Endothelin B,
pubmed-meshheading:20710019-Splanchnic Circulation,
pubmed-meshheading:20710019-Sulfones,
pubmed-meshheading:20710019-Sus scrofa,
pubmed-meshheading:20710019-Tetrazoles,
pubmed-meshheading:20710019-Vasodilator Agents
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pubmed:year |
2010
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pubmed:articleTitle |
Endothelin-mediated gut microcirculatory dysfunction during porcine endotoxaemia.
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pubmed:affiliation |
Department of Anaesthesiology and Intensive Care, Karolinska University Hospital, Huddinge, Sweden. andreas.andersson@karolinska.se
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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