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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1-2
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pubmed:dateCreated |
2010-11-29
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pubmed:abstractText |
Clarifying the aetiology of dementia is of crucial importance in the management of patients as well as for research purposes but it is not always possible clinically. Therefore the identification of biological markers should complement clinical approaches. Telomere shortening is emerging as an important mechanism in vascular aging and the pathogenesis of hypertension and atherosclerosis. Thus, telomere length could be a potential candidate to accurately separate vascular from degenerative cognitive impairment.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1878-5883
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2010 Elsevier B.V. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:day |
15
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pubmed:volume |
299
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
108-11
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pubmed:meshHeading |
pubmed-meshheading:20709332-Aged,
pubmed-meshheading:20709332-Aged, 80 and over,
pubmed-meshheading:20709332-Alleles,
pubmed-meshheading:20709332-Alzheimer Disease,
pubmed-meshheading:20709332-Analysis of Variance,
pubmed-meshheading:20709332-Apolipoproteins E,
pubmed-meshheading:20709332-Cognition Disorders,
pubmed-meshheading:20709332-Dementia, Vascular,
pubmed-meshheading:20709332-Female,
pubmed-meshheading:20709332-Flow Cytometry,
pubmed-meshheading:20709332-Gene Frequency,
pubmed-meshheading:20709332-Humans,
pubmed-meshheading:20709332-In Situ Hybridization,
pubmed-meshheading:20709332-Logistic Models,
pubmed-meshheading:20709332-Longitudinal Studies,
pubmed-meshheading:20709332-Male,
pubmed-meshheading:20709332-Neuropsychological Tests,
pubmed-meshheading:20709332-Polymorphism, Genetic,
pubmed-meshheading:20709332-Telomere
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pubmed:year |
2010
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pubmed:articleTitle |
Telomere length and ApoE polymorphism in mild cognitive impairment, degenerative and vascular dementia.
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pubmed:affiliation |
Geneva University, Rehabilitation and Geriatrics Department, Thônex, Switzerland. dina.zekry@hcuge.ch
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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