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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
18
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pubmed:dateCreated |
2010-11-29
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pubmed:abstractText |
To estimate the maximum-tolerated dose (MTD); study the pharmacology of escalating doses of gefitinib combined with radiation therapy in patients ?21 years with newly diagnosed intrinsic brainstem gliomas (BSG) and incompletely resected supratentorial malignant gliomas (STMG); and to investigate epidermal growth factor receptor (EGFR) amplification and expression in STMG.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1879-0852
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pubmed:author |
pubmed-author:BanerjeeAnuA,
pubmed-author:BlaneySusan MSM,
pubmed-author:BoyettJames MJM,
pubmed-author:BroniscerAlbertoA,
pubmed-author:DouglasJames GJG,
pubmed-author:GeyerJ RussellJR,
pubmed-author:GilbertsonRichard JRJ,
pubmed-author:GururanganSriS,
pubmed-author:KieranMark WMW,
pubmed-author:KocakMehmetM,
pubmed-author:KunLarry ELE,
pubmed-author:PackerRoger JRJ,
pubmed-author:PhillipsPeterP,
pubmed-author:StewartClinton FCF
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pubmed:copyrightInfo |
Copyright © 2010 Elsevier Ltd. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
46
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3287-93
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pubmed:meshHeading |
pubmed-meshheading:20708924-Adolescent,
pubmed-meshheading:20708924-Antineoplastic Agents,
pubmed-meshheading:20708924-Brain Stem Neoplasms,
pubmed-meshheading:20708924-Child,
pubmed-meshheading:20708924-Child, Preschool,
pubmed-meshheading:20708924-Combined Modality Therapy,
pubmed-meshheading:20708924-Female,
pubmed-meshheading:20708924-Glioma,
pubmed-meshheading:20708924-Humans,
pubmed-meshheading:20708924-Male,
pubmed-meshheading:20708924-Maximum Tolerated Dose,
pubmed-meshheading:20708924-Quinazolines,
pubmed-meshheading:20708924-Receptor, Epidermal Growth Factor,
pubmed-meshheading:20708924-Supratentorial Neoplasms,
pubmed-meshheading:20708924-Young Adult
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pubmed:year |
2010
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pubmed:articleTitle |
A phase I and biology study of gefitinib and radiation in children with newly diagnosed brain stem gliomas or supratentorial malignant gliomas.
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pubmed:affiliation |
Seattle Children's Hospital, Seattle, WA, USA.
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pubmed:publicationType |
Journal Article,
Clinical Trial, Phase I,
Research Support, N.I.H., Extramural
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