rdf:type |
|
lifeskim:mentions |
umls-concept:C0005516,
umls-concept:C0017982,
umls-concept:C0030705,
umls-concept:C0079809,
umls-concept:C0138741,
umls-concept:C0205217,
umls-concept:C0242485,
umls-concept:C0332324,
umls-concept:C0376358,
umls-concept:C1510438,
umls-concept:C1704272,
umls-concept:C1707455
|
pubmed:issue |
23-24
|
pubmed:dateCreated |
2010-10-11
|
pubmed:abstractText |
Prostate specific antigen (PSA) measurement is used for the diagnosis of prostate cancer (PCa) but the test lacks specificity due to the number of false positive readings. The glycosylation of PSA is altered in PCa but studies in this area have been limited to few clinical samples and/or require advanced laboratory facilities. An assay to assess PSA glycosylation was established using equipment available in most routine biomedical testing laboratories.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
1873-3492
|
pubmed:author |
|
pubmed:copyrightInfo |
Copyright © 2010 Elsevier B.V. All rights reserved.
|
pubmed:issnType |
Electronic
|
pubmed:day |
14
|
pubmed:volume |
411
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1935-9
|
pubmed:meshHeading |
pubmed-meshheading:20708609-Aged,
pubmed-meshheading:20708609-Aged, 80 and over,
pubmed-meshheading:20708609-Biological Markers,
pubmed-meshheading:20708609-Blood Chemical Analysis,
pubmed-meshheading:20708609-Fucose,
pubmed-meshheading:20708609-Glycosylation,
pubmed-meshheading:20708609-Humans,
pubmed-meshheading:20708609-Immunoassay,
pubmed-meshheading:20708609-Male,
pubmed-meshheading:20708609-Middle Aged,
pubmed-meshheading:20708609-Plant Lectins,
pubmed-meshheading:20708609-Prostate-Specific Antigen,
pubmed-meshheading:20708609-Prostatic Hyperplasia,
pubmed-meshheading:20708609-Prostatic Neoplasms
|
pubmed:year |
2010
|
pubmed:articleTitle |
A sensitive assay to measure biomarker glycosylation demonstrates increased fucosylation of prostate specific antigen (PSA) in patients with prostate cancer compared with benign prostatic hyperplasia.
|
pubmed:affiliation |
Department of Molecular and Applied Biosciences, University of Westminster, London, UK. m.v.dwek@westminster.ac.uk
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|