Source:http://linkedlifedata.com/resource/pubmed/id/20706913
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
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pubmed:dateCreated |
2010-8-13
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pubmed:abstractText |
A new ganoderic acid (GA), 7-O-ethyl ganoderic acid O (GA-O) (1), together with two known compounds, GA-T (2) and GA-Me (3), was isolated and purified from fermented mycelia of Ganoderma lucidum. The structure of the new triterpenoid was elucidated on the basis of the interpretation of extensive spectroscopic data (HR-MS, IR, UV, 1D and 2D NMR) as 3 alpha,15 alpha,22-triacetoxy-7 alpha-ethoxy-5 alpha-lanost-8,24E-dien-26-oic acid. The new compound was found to contain a rare ethoxyl group at C-7. In addition, its cytotoxicity against 95D and HeLa human cancer cell lines was also evaluated.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1477-2213
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
727-30
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pubmed:meshHeading |
pubmed-meshheading:20706913-China,
pubmed-meshheading:20706913-Drug Screening Assays, Antitumor,
pubmed-meshheading:20706913-Female,
pubmed-meshheading:20706913-HeLa Cells,
pubmed-meshheading:20706913-Humans,
pubmed-meshheading:20706913-Lanosterol,
pubmed-meshheading:20706913-Molecular Structure,
pubmed-meshheading:20706913-Mycelium,
pubmed-meshheading:20706913-Nuclear Magnetic Resonance, Biomolecular,
pubmed-meshheading:20706913-Reishi
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pubmed:year |
2010
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pubmed:articleTitle |
A new ganoderic acid from Ganoderma lucidum mycelia.
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pubmed:affiliation |
Key Laboratory of Microbial Metabolism, Ministry of Education, School of Life Sciences & Biotechnology, Shanghai Jiao Tong University, Shanghai, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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