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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1991-8-16
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pubmed:abstractText |
This report describes the authors' experience with salvage surgery in 78 patients with carcinoma of the buccal mucosa who failed after high-dose radical radiation therapy at Regional Cancer Centre, Trivandrum, India. Forty-four patients (56%) required a hemimandibulectomy for adequate tumor clearance. Fifty-four patients (69%) required a primary reconstructive procedure for wound closure. Follow-up periods ranged from 28 months to 63 months (median follow-up, 41 months). Thirteen patients (17%) developed nonfatal postoperative complications. Thirty-one patients recurred after surgery, five of whom were again salvaged by further surgery. Overall, the recurrence rate was 36%. Most of the recurrences (26/31) were at the primary site. The overall 5-year actuarial disease-free survival after salvage surgery was 59.7%. T stage of the recurrent tumor and its skin infiltration emerged as factors which significantly influenced disease-free survival (P less than 0.05).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0008-543X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
68
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
295-9
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:2070328-Adult,
pubmed-meshheading:2070328-Aged,
pubmed-meshheading:2070328-Aged, 80 and over,
pubmed-meshheading:2070328-Carcinoma, Squamous Cell,
pubmed-meshheading:2070328-Combined Modality Therapy,
pubmed-meshheading:2070328-Female,
pubmed-meshheading:2070328-Follow-Up Studies,
pubmed-meshheading:2070328-Humans,
pubmed-meshheading:2070328-Lymphatic Metastasis,
pubmed-meshheading:2070328-Male,
pubmed-meshheading:2070328-Middle Aged,
pubmed-meshheading:2070328-Mouth Neoplasms,
pubmed-meshheading:2070328-Neoplasm Recurrence, Local,
pubmed-meshheading:2070328-Neoplasm Staging,
pubmed-meshheading:2070328-Postoperative Complications,
pubmed-meshheading:2070328-Survival Rate
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pubmed:year |
1991
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pubmed:articleTitle |
Evaluation of salvage surgery in heavily irradiated cancer of the buccal mucosa.
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pubmed:affiliation |
Regional Cancer Centre, Trivandrum, Kerala, India.
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pubmed:publicationType |
Journal Article
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