Source:http://linkedlifedata.com/resource/pubmed/id/20698837
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
2010-11-22
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pubmed:abstractText |
Significant evidence has accumulated to suggest an association between single-nucleotide polymorphisms (SNPs) in the GABRA2 gene and alcoholism. However, research has yet to show an association between these polymorphisms and the human brain's reward system function. In this study, we stratified subjects who had participated in an fMRI study of alcohol cue responses according to their genotype at a SNP in GABRA2 (rs279871) shown to be associated with alcohol dependence (Edenberg et al., 2004).
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1530-0277
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pubmed:author | |
pubmed:copyrightInfo |
Copyright © 2010 by the Research Society on Alcoholism.
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pubmed:issnType |
Electronic
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pubmed:volume |
34
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2169-78
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pubmed:meshHeading |
pubmed-meshheading:20698837-Adult,
pubmed-meshheading:20698837-Alcoholic Intoxication,
pubmed-meshheading:20698837-Alcoholism,
pubmed-meshheading:20698837-Alleles,
pubmed-meshheading:20698837-Behavior, Addictive,
pubmed-meshheading:20698837-Brain Mapping,
pubmed-meshheading:20698837-Cues,
pubmed-meshheading:20698837-Ethanol,
pubmed-meshheading:20698837-Female,
pubmed-meshheading:20698837-Genotype,
pubmed-meshheading:20698837-Humans,
pubmed-meshheading:20698837-Magnetic Resonance Imaging,
pubmed-meshheading:20698837-Male,
pubmed-meshheading:20698837-Odors,
pubmed-meshheading:20698837-Polymorphism, Single Nucleotide,
pubmed-meshheading:20698837-Prefrontal Cortex,
pubmed-meshheading:20698837-Receptors, GABA-A
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pubmed:year |
2010
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pubmed:articleTitle |
A polymorphism in GABRA2 is associated with the medial frontal response to alcohol cues in an fMRI study.
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pubmed:affiliation |
Department of Neurology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA. dkareken@iupui.edu
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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