Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1991-8-20
pubmed:abstractText
Lymphatic filariasis is manifested by a spectrum of symptoms that range from microfilaraemia to gross immunopathology. The geographical variations seen in this disease have been explained by heterogeneity in genetically determined host responses. By modelling the disease through time, Don Bundy, Bryan Grenfell and P.K. Rajagopalan can provide a simple, unified explanation for the observed heterogeneity. Their model shows that there is a sequential progression from infection, microfilaraemia, amicrofilaraemia to obstructive disease in all individuals who experience microfilaraemia. Only the probability of developing microfilaraemia is geographically variable, being dependent on the local incidence of infection.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0167-5699
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
A71-5
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Immunoepidemiology of lymphatic filariasis: the relationship between infection and disease.
pubmed:affiliation
Wellcome Trust Research Centre for Parasitic Infections, Imperial College of Science, Technology and Medicine, London, UK.
pubmed:publicationType
Journal Article, Review