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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1991-8-15
|
| pubmed:abstractText |
One hundred consecutive patients with the Marfan syndrome underwent composite graft repair of an ascending aortic aneurysm between September 1976 and June 1989. Twenty-two patients had ascending aortic dissection at the time of composite graft repair; 18 patients also had a mitral valve procedure. There were no hospital deaths among 92 patients undergoing elective repair. One of 8 patients undergoing emergency repair of a ruptured aneurysm died in the operating room. The overall hospital mortality rate was 1%. There have been ten late deaths among the 99 hospital survivors (10.1%). Five deaths occurred among the first 11 patients in this series and five occurred among the last 88 patients (5.7%). Three late deaths resulted from composite graft endocarditis; 3 other patients with endocarditis are alive after aortic root replacement with cryopreserved homografts. Late coronary dehiscence caused death in 1 patient and was successfully repaired in a second. Actuarial survival for the 100 patients was 92.6% at 5 years and 75.8% at 10 years. Currently, composite graft repair of Marfan aneurysms of the ascending aorta can be performed with low hospital and late mortality. Marfan aneurysms with a diameter of 6 cm or greater should be repaired with the Bentall composite graft procedure, even if the patient is asymptomatic.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jul
|
| pubmed:issn |
0003-4975
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
52
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
38-44; discussion 44-5
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:2069460-Adolescent,
pubmed-meshheading:2069460-Adult,
pubmed-meshheading:2069460-Aged,
pubmed-meshheading:2069460-Aneurysm, Dissecting,
pubmed-meshheading:2069460-Aortic Aneurysm,
pubmed-meshheading:2069460-Aortic Rupture,
pubmed-meshheading:2069460-Blood Vessel Prosthesis,
pubmed-meshheading:2069460-Cause of Death,
pubmed-meshheading:2069460-Child,
pubmed-meshheading:2069460-Female,
pubmed-meshheading:2069460-Follow-Up Studies,
pubmed-meshheading:2069460-Humans,
pubmed-meshheading:2069460-Male,
pubmed-meshheading:2069460-Marfan Syndrome,
pubmed-meshheading:2069460-Middle Aged,
pubmed-meshheading:2069460-Postoperative Care,
pubmed-meshheading:2069460-Postoperative Complications,
pubmed-meshheading:2069460-Risk Factors,
pubmed-meshheading:2069460-Surgical Wound Dehiscence,
pubmed-meshheading:2069460-Survival Rate
|
| pubmed:year |
1991
|
| pubmed:articleTitle |
Composite graft repair of Marfan aneurysm of the ascending aorta: results in 100 patients.
|
| pubmed:affiliation |
Division of Cardiac Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|