Source:http://linkedlifedata.com/resource/pubmed/id/20693616
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
35
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pubmed:dateCreated |
2010-8-9
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pubmed:abstractText |
We demonstrated enhanced localized surface plasmon resonance (SPR) biosensing based on subwavelength gold nanoarrays built on a thin gold film. Arrays of nanogratings (1D) and nanoholes (2D) with a period of 200 nm were fabricated by electron-beam lithography and used for the detection of avian influenza DNA hybridization. Experimental results showed that both nanoarrays provided significant sensitivity improvement and, especially, 1D nanogratings exhibited higher SPR signal amplification compared with 2D nanohole arrays. The sensitivity enhancement is associated with changes in surface-limited reaction area and strong interactions between bound molecules and localized plasmon fields. Our approach is expected to improve both the sensitivity and sensing resolution and can be applicable to label-free detection of DNA without amplification by polymerase chain reaction.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1361-6528
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pubmed:author |
pubmed-author:ByunKyung MinKM,
pubmed-author:JangSeong MinSM,
pubmed-author:JangSung MinSM,
pubmed-author:KimDonghyunD,
pubmed-author:KimKyujungK,
pubmed-author:KimShin AeSA,
pubmed-author:KimSung GukSG,
pubmed-author:KimSung JuneSJ,
pubmed-author:MaKyungjaeK,
pubmed-author:OhYoungjinY,
pubmed-author:ShulerMichael LML
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pubmed:issnType |
Electronic
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pubmed:day |
3
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
355503
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pubmed:dateRevised |
2011-7-29
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pubmed:meshHeading |
pubmed-meshheading:20693616-Biosensing Techniques,
pubmed-meshheading:20693616-DNA, Viral,
pubmed-meshheading:20693616-Gold,
pubmed-meshheading:20693616-Influenza A virus,
pubmed-meshheading:20693616-Nanotechnology,
pubmed-meshheading:20693616-Nucleic Acid Hybridization,
pubmed-meshheading:20693616-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:20693616-Sensitivity and Specificity,
pubmed-meshheading:20693616-Surface Plasmon Resonance
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pubmed:year |
2010
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pubmed:articleTitle |
Surface-enhanced localized surface plasmon resonance biosensing of avian influenza DNA hybridization using subwavelength metallic nanoarrays.
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pubmed:affiliation |
School of Electrical Engineering and Computer Science, Seoul National University, Seoul, Korea.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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