Linked Life Data

20691429

Source:http://linkedlifedata.com/resource/pubmed/id/20691429

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
2010-10-15
pubmed:abstractText
Attention-deficit/hyperactivity disorder is a psychiatric disorder that starts in childhood. The mechanism of action of methylphenidate, the most common treatment for attention deficit hyperactivity disorder, is unclear. In vitro, the affinity of methylphenidate for the norepinephrine transporter (NET) is higher than that for the dopamine transporter (DAT). The goal of this study was to use positron emission tomography to measure the occupancy of brain norepinephrine transporter by methylphenidate in vivo in humans.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1873-2402
pubmed:author
pubmed:copyrightInfo
Copyright © 2010 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.
pubmed:issnType
Electronic
pubmed:day
1
pubmed:volume
68
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
854-60
pubmed:dateRevised
2011-9-22
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Clinically relevant doses of methylphenidate significantly occupy norepinephrine transporters in humans in vivo.
pubmed:affiliation
Department of Psychiatry, Yale PET Center, Yale University School of Medicine, New Haven, Connecticut, USA.
pubmed:publicationType
Journal Article, Clinical Trial, Research Support, N.I.H., Extramural