Linked Life Data

20686177

Source:http://linkedlifedata.com/resource/pubmed/id/20686177

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
43
pubmed:dateCreated
2010-8-5
pubmed:abstractText
Once Pandora unlocked her fateful box and liberated the evil forces within, it became impossible to put them back. Now, new work on Crohn's disease suggests the existence of a viral "key" that irreversibly renders a genetically susceptible mouse prone to pathogenesis. Indeed, dangerous liaisons among host genotype, viral infection, intestinal injury, and trillions of gut microbes may in part determine which individuals progress to a full-blown disease state. These findings suggest that viral and bacterial triggers may serve as therapeutic targets for Crohn's and prompt new hypotheses that relate inflammation, host immune status, microbial community structure, and human health.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1946-6242
pubmed:author
pubmed:issnType
Electronic
pubmed:day
4
pubmed:volume
2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
43ps39
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
A microbe-dependent viral key to Crohn's box.
pubmed:affiliation
Department of Food Science and Technology, University of Nebraska, Lincoln, NE 68583, USA.
pubmed:publicationType
Journal Article