Linked Life Data

20684207

Source:http://linkedlifedata.com/resource/pubmed/id/20684207

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2010-8-5
pubmed:abstractText
The definitive diagnosis of idiopathic pulmonary fibrosis (IPF) requires a pathologic pattern of usual interstitial pneumonia (UIP). However, it is not clear that whether there is a difference in outcome between patients with IPF diagnosed by clinical findings, and those diagnosed by pathological findings. We investigated differences in survival between patients diagnosed with IPF based on clinical findings, and patients who underwent surgical biopsy for a pathological diagnosis of IPF/UIP based on findings showing a UIP pattern. Sixty-one patients who received a clinical diagnosis of IPF were selected by random sampling. Fifty-nine patients underwent open lung biopsy or video assisted thoracoscopic biopsy and receive a pathological diagnosis of IPF/UIP. At diagnosis, 23 clinical features were identified and the hazard ratio of pathological diagnosis was estimated using the Cox proportional hazard model adjusted for those features that differed between the two groups. The adjusted hazard ratio of pathological diagnosis, taking these factors into account, was 1.09 (95% confidence interval, 0.42 to 2.80, p = 0.861) to about 1.0. Therefore, it is reasonable to diagnose IPF based on clinical findings from the perspective of outcome.
pubmed:language
jpn
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1343-3490
pubmed:author
pubmed:issnType
Print
pubmed:volume
48
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
469-74
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
[The influence of pathological diagnosis on outcome in patients with idiopathic pulmonary fibrosis].
pubmed:affiliation
Second Department of Internal Medicine, Hamamatsu University School of Medicine.
pubmed:publicationType
Journal Article, English Abstract