Source:http://linkedlifedata.com/resource/pubmed/id/20683254
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
2010-8-27
|
| pubmed:abstractText |
Local anesthetics offer the benefits of extended analgesia with greater patient satisfaction and faster rehabilitation compared with intravenous morphine. These benefits, however, can be offset by adverse iatrogenic muscle pain. Here, the authors investigate the mechanisms of local anesthetic-induced myotoxicity and assess the protective effect of N-acetylcysteine.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Sep
|
| pubmed:issn |
1528-1175
|
| pubmed:author | |
| pubmed:issnType |
Electronic
|
| pubmed:volume |
113
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
560-9
|
| pubmed:meshHeading |
pubmed-meshheading:20683254-Acetylcysteine,
pubmed-meshheading:20683254-Antioxidants,
pubmed-meshheading:20683254-Apoptosis,
pubmed-meshheading:20683254-Bupivacaine,
pubmed-meshheading:20683254-Cells, Cultured,
pubmed-meshheading:20683254-Humans,
pubmed-meshheading:20683254-Muscle, Skeletal,
pubmed-meshheading:20683254-Muscle Fibers, Skeletal,
pubmed-meshheading:20683254-Oxidative Stress,
pubmed-meshheading:20683254-Reactive Oxygen Species,
pubmed-meshheading:20683254-Sarcoplasmic Reticulum
|
| pubmed:year |
2010
|
| pubmed:articleTitle |
N-acetylcysteine protects against bupivacaine-induced myotoxicity caused by oxidative and sarcoplasmic reticulum stress in human skeletal myotubes.
|
| pubmed:affiliation |
Institut National de la Recherche Agronomique (INRA), UMR866, Differenciation Cellulaire et Croissance, Montpellier, France.
|
| pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|