20682712

Source:http://linkedlifedata.com/resource/pubmed/id/20682712

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0005516, umls-concept:C0017337, umls-concept:C0162789, umls-concept:C0441655, umls-concept:C1510941, umls-concept:C1514292, umls-concept:C1527249, umls-concept:C1706679, umls-concept:C1999216, umls-concept:C2828242
pubmed:issue	16
pubmed:dateCreated	2010-8-13
pubmed:abstractText	To evaluate the efficacy of saracatinib (AZD0530), an oral Src inhibitor, in colorectal cancer (CRC) and to identify biomarkers that predict antitumor activity.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9502500
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents, http://linkedlifedata.com/resource/pubmed/chemical/Benzodioxoles, http://linkedlifedata.com/resource/pubmed/chemical/N-(5-chloro-1,3-benzodioxol-4-yl)-7-..., http://linkedlifedata.com/resource/pubmed/chemical/Protein Kinase Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Quinazolines, http://linkedlifedata.com/resource/pubmed/chemical/Tumor Markers, Biological
pubmed:status	MEDLINE
pubmed:month	Aug
pubmed:issn	1078-0432
pubmed:author	pubmed-author:ArcaroliJohn JJJ, pubmed-author:EckhardtS GailSG, pubmed-author:ElvinPaulP, pubmed-author:GaoDexiangD, pubmed-author:MessersmithWells AWA, pubmed-author:PowellRebecca WRW, pubmed-author:TanAik ChoonAC, pubmed-author:ToubanBasel MBM, pubmed-author:Varella-GarciaMarileilaM
pubmed:issnType	Print
pubmed:day	15
pubmed:volume	16
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	4165-77
pubmed:meshHeading	pubmed-meshheading:20682712-Animals, pubmed-meshheading:20682712-Antineoplastic Agents, pubmed-meshheading:20682712-Apoptosis, pubmed-meshheading:20682712-Benzodioxoles, pubmed-meshheading:20682712-Cell Line, Tumor, pubmed-meshheading:20682712-Cell Proliferation, pubmed-meshheading:20682712-Cell Separation, pubmed-meshheading:20682712-Colorectal Neoplasms, pubmed-meshheading:20682712-Drug Resistance, Neoplasm, pubmed-meshheading:20682712-Flow Cytometry, pubmed-meshheading:20682712-Humans, pubmed-meshheading:20682712-Immunoblotting, pubmed-meshheading:20682712-Immunohistochemistry, pubmed-meshheading:20682712-In Situ Hybridization, Fluorescence, pubmed-meshheading:20682712-Mice, pubmed-meshheading:20682712-Oligonucleotide Array Sequence Analysis, pubmed-meshheading:20682712-Protein Kinase Inhibitors, pubmed-meshheading:20682712-Quinazolines, pubmed-meshheading:20682712-Tumor Markers, Biological, pubmed-meshheading:20682712-Xenograft Model Antitumor Assays
pubmed:year	2010
pubmed:articleTitle	Gene array and fluorescence in situ hybridization biomarkers of activity of saracatinib (AZD0530), a Src inhibitor, in a preclinical model of colorectal cancer.
pubmed:affiliation	Division of Medical Oncology, University of Colorado, Denver, Colorado, USA.
pubmed:publicationType	Journal Article