Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
2010-9-29
pubmed:abstractText
Olanzapine (OLZ) is an atypical antipsychotic whose clinical efficacy is hampered by side effects including weight gain and diabetes. Recent evidence shows that OLZ alters insulin sensitivity independent of changes in body weight and composition. The present study addresses whether OLZ-induced insulin resistance is driven by its central actions.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1939-327X
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
59
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2418-25
pubmed:meshHeading
pubmed-meshheading:20682682-Animals, pubmed-meshheading:20682682-Antipsychotic Agents, pubmed-meshheading:20682682-Benzodiazepines, pubmed-meshheading:20682682-Blood Glucose, pubmed-meshheading:20682682-Carotid Arteries, pubmed-meshheading:20682682-DNA Primers, pubmed-meshheading:20682682-Glucose Clamp Technique, pubmed-meshheading:20682682-Glucose-6-Phosphatase, pubmed-meshheading:20682682-Hyperinsulinism, pubmed-meshheading:20682682-Infusions, Intravenous, pubmed-meshheading:20682682-Injections, Intraventricular, pubmed-meshheading:20682682-Insulin Resistance, pubmed-meshheading:20682682-Intracellular Signaling Peptides and Proteins, pubmed-meshheading:20682682-Jugular Veins, pubmed-meshheading:20682682-Kinetics, pubmed-meshheading:20682682-Liver, pubmed-meshheading:20682682-Male, pubmed-meshheading:20682682-Neuropeptides, pubmed-meshheading:20682682-Pro-Opiomelanocortin, pubmed-meshheading:20682682-Rats, pubmed-meshheading:20682682-Rats, Sprague-Dawley, pubmed-meshheading:20682682-Tubulin
pubmed:year
2010
pubmed:articleTitle
Central nervous system delivery of the antipsychotic olanzapine induces hepatic insulin resistance.
pubmed:affiliation
Obesity Research Center, University of Cincinnati, Cincinnati, Ohio, USA.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't