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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2010-11-1
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pubmed:abstractText |
Stress signaling, both within and outside the endoplasmic reticulum, has been linked to metabolic dysregulation and hepatic steatosis. Methionine-choline-deficient (MCD) diets cause severe fatty liver disease and have the potential to cause many types of cellular stress. The purpose of this study was to characterize hepatic stress in MCD-fed mice and explore the relationship between MCD-mediated stress and liver injury.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1528-0012
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2010 AGA Institute. Published by Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
139
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1730-9, 1739.e1
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pubmed:dateRevised |
2011-11-1
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pubmed:meshHeading |
pubmed-meshheading:20682321-Animals,
pubmed-meshheading:20682321-Apoptosis,
pubmed-meshheading:20682321-Blotting, Western,
pubmed-meshheading:20682321-Caspase 12,
pubmed-meshheading:20682321-Choline Deficiency,
pubmed-meshheading:20682321-DNA-Binding Proteins,
pubmed-meshheading:20682321-Disease Models, Animal,
pubmed-meshheading:20682321-Fatty Liver,
pubmed-meshheading:20682321-Genes, MHC Class II,
pubmed-meshheading:20682321-JNK Mitogen-Activated Protein Kinases,
pubmed-meshheading:20682321-Liver,
pubmed-meshheading:20682321-Male,
pubmed-meshheading:20682321-Methionine,
pubmed-meshheading:20682321-Mice,
pubmed-meshheading:20682321-Mice, Inbred C3H,
pubmed-meshheading:20682321-Oxidative Stress,
pubmed-meshheading:20682321-Signal Transduction,
pubmed-meshheading:20682321-Transcription Factors,
pubmed-meshheading:20682321-Triglycerides
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pubmed:year |
2010
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pubmed:articleTitle |
Stress signaling in the methionine-choline-deficient model of murine fatty liver disease.
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pubmed:affiliation |
Department of Medicine, The Liver Center, University of California, San Francisco, California, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, N.I.H., Extramural
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