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rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2011-5-11
pubmed:abstractText
To assess the diagnostic accuracy of prospective ECG-triggering 64-slice multidetector computed tomography (MDCT) coronary angiography for evaluation of coronary artery disease (CAD). Forty-two patients (31 males, 11 females, mean age 64 years) underwent cardiac CT and invasive coronary angiography (ICA). Patients with a heart rate of <65 beats/min with stable heart rhythm were included in the study sample. We used a prospective ECG-triggering protocol. Luminal narrowing over 50% was considered to be significant according to a modified 17-segment AHA model, using invasive coronary angiography (ICA) as the standard of reference. The mean radiation dose was 3.5 mSv ± 0.3 (range, 3.3-4.2 mSv), and 542 of 549 segments (98.7%) in the 42 patients were diagnostic. In contrast, 119 of 542 segments (22%) were diagnosed as significant by ICA. The sensitivity, specificity, accuracy, PPV and NPV were 95.0, 96.2, 96, 85.8 and 98.8%, respectively. False positive results were affected by densely calcified plaques, whereas false negatives were caused by motion artifact with poor vessel attenuation at the distal segments or near the bifurcation area of the coronary arteries. Prospective ECG-triggering MDCT is a useful method for evaluating CAD in patients with a lower heart rate with low radiation dose.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1875-8312
pubmed:author
pubmed:copyrightInfo
© Springer Science+Business Media, B.V. 2010
pubmed:issnType
Electronic
pubmed:volume
27
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
425-31
pubmed:meshHeading
pubmed-meshheading:20680462-Aged, pubmed-meshheading:20680462-Artifacts, pubmed-meshheading:20680462-Calcinosis, pubmed-meshheading:20680462-Cardiac-Gated Imaging Techniques, pubmed-meshheading:20680462-Coronary Angiography, pubmed-meshheading:20680462-Coronary Stenosis, pubmed-meshheading:20680462-Electrocardiography, pubmed-meshheading:20680462-False Negative Reactions, pubmed-meshheading:20680462-False Positive Reactions, pubmed-meshheading:20680462-Female, pubmed-meshheading:20680462-Heart Rate, pubmed-meshheading:20680462-Humans, pubmed-meshheading:20680462-Male, pubmed-meshheading:20680462-Middle Aged, pubmed-meshheading:20680462-Observer Variation, pubmed-meshheading:20680462-Predictive Value of Tests, pubmed-meshheading:20680462-Prospective Studies, pubmed-meshheading:20680462-Radiation Dosage, pubmed-meshheading:20680462-Reproducibility of Results, pubmed-meshheading:20680462-Republic of Korea, pubmed-meshheading:20680462-Severity of Illness Index, pubmed-meshheading:20680462-Tomography, X-Ray Computed
pubmed:year
2011
pubmed:articleTitle
Low-dose coronary computed tomography angiography using prospective ECG-triggering compared to invasive coronary angiography.
pubmed:affiliation
Department of Radiology and Research Institute of Radiological Science, Yonsei University Health System, Seoul 135-720, Republic of Korea.
pubmed:publicationType
Journal Article