Linked Life Data

2067989

Source:http://linkedlifedata.com/resource/pubmed/id/2067989

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1991-8-14
pubmed:abstractText
The purpose of this study was to determine the distribution of VIP binding sites in the thymus and bursa of Fabricius using receptor binding and autoradiographic techniques. Biochemical characterization of 125I-VIP binding sites determined two classes of specific binding sites in both tissues. The dissociation constants determined in the thymus were 1.12 nM and 88.5 nM, and in the bursa were 0.459 nM and 70.8 nM. Autoradiographic localization of 125I-VIP binding sites within the thymus demonstrated specific binding associated with the medullary region of the thymic lobule and the blood vessels in the interlobular and trabecular areas. Within the bursa of Fabricius, high densities of silver grains corresponded with vascular elements in the interfollicular regions, the epithelial border of the plicae, the muscular layer surrounding the organ, and the diffusely infiltrated area near the burso-cloacal duct.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0196-9781
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
383-91
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:articleTitle
Localization of vasoactive intestinal peptide binding sites in the thymus and bursa of Fabricius of the chick.
pubmed:affiliation
Department of Cell Biology and Neuroanatomy, University of Minnesota, Minneapolis 55455.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't