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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1991-8-12
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pubmed:abstractText |
We report a retrospective study of invasive Haemophilus influenzae type b (Hib) diseases in Geneva from 1976 to 1989. Among the 183 children who fulfilled the case definition, 6 (3.3%) presented with more than one site of infection. The overall incidence rate among children younger than 5 years of age was 60.2/100,000 but it was 92.1/100,000 in 1989. Forty-one percent of patients had meningitis, 37% had epiglottis and 22% had other forms of Hib infections. Fifty-four percent of cases occurred in children younger than 2 years of age. Invasive Hib infections were found more often in boys than in girls (1.6/1). From 1984, 21% of all Hib were beta-lactamase-producing strains. During the study period 2 children (1.1%) died from epiglottitis and 12 children with meningitis (15.8%) developed serious neurologic deficits. These data suggest that administration of a conjugate vaccine against Hib to all infants living in Geneva is justified.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0891-3668
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
370-4
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2067887-Age Factors,
pubmed-meshheading:2067887-Chi-Square Distribution,
pubmed-meshheading:2067887-Child,
pubmed-meshheading:2067887-Child, Preschool,
pubmed-meshheading:2067887-Epiglottitis,
pubmed-meshheading:2067887-Female,
pubmed-meshheading:2067887-Haemophilus Infections,
pubmed-meshheading:2067887-Haemophilus influenzae,
pubmed-meshheading:2067887-Humans,
pubmed-meshheading:2067887-Incidence,
pubmed-meshheading:2067887-Infant,
pubmed-meshheading:2067887-Male,
pubmed-meshheading:2067887-Meningitis, Haemophilus,
pubmed-meshheading:2067887-Regression Analysis,
pubmed-meshheading:2067887-Retrospective Studies,
pubmed-meshheading:2067887-Seasons,
pubmed-meshheading:2067887-Sex Factors,
pubmed-meshheading:2067887-Switzerland
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pubmed:year |
1991
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pubmed:articleTitle |
Epidemiology of invasive Haemophilus influenzae type b infections in Geneva, Switzerland, 1976 to 1989.
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pubmed:affiliation |
Children's Hospital, Department of Pediatrics, University of Geneva, Switzerland.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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