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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2010-10-4
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pubmed:abstractText |
Mesenteric ischemia-reperfusion injury (IRI) leads to systemic inflammation and multiple organ failure in clinical and laboratory settings. We investigated the lung structural, functional, and genomic response to mesenteric IRI with and without regional intraischemic hypothermia (RIH) in rodents and hypothesized that RIH would protect the lung and preferentially modulate the distant organ transcriptome under these conditions.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1097-6809
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2010 Society for Vascular Surgery. Published by Mosby, Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
52
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1003-14
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pubmed:dateRevised |
2011-10-3
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pubmed:meshHeading |
pubmed-meshheading:20678877-Animals,
pubmed-meshheading:20678877-Bronchoalveolar Lavage Fluid,
pubmed-meshheading:20678877-Cell Adhesion,
pubmed-meshheading:20678877-Chemotaxis, Leukocyte,
pubmed-meshheading:20678877-Cluster Analysis,
pubmed-meshheading:20678877-Disease Models, Animal,
pubmed-meshheading:20678877-Gene Expression Profiling,
pubmed-meshheading:20678877-Gene Expression Regulation,
pubmed-meshheading:20678877-Hypothermia, Induced,
pubmed-meshheading:20678877-Immunity, Innate,
pubmed-meshheading:20678877-Inflammation Mediators,
pubmed-meshheading:20678877-Lung,
pubmed-meshheading:20678877-Male,
pubmed-meshheading:20678877-Mesenteric Vascular Occlusion,
pubmed-meshheading:20678877-Neutrophil Activation,
pubmed-meshheading:20678877-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:20678877-Pneumonia,
pubmed-meshheading:20678877-Polymerase Chain Reaction,
pubmed-meshheading:20678877-Pulmonary Edema,
pubmed-meshheading:20678877-Rats,
pubmed-meshheading:20678877-Rats, Sprague-Dawley,
pubmed-meshheading:20678877-Reperfusion Injury,
pubmed-meshheading:20678877-Reproducibility of Results,
pubmed-meshheading:20678877-Time Factors
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pubmed:year |
2010
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pubmed:articleTitle |
Therapeutic distant organ effects of regional hypothermia during mesenteric ischemia-reperfusion injury.
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pubmed:affiliation |
Department of Surgery, The Methodist Hospital and Research Institute, Houston, Tex, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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