Source:http://linkedlifedata.com/resource/pubmed/id/20677847
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
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| pubmed:dateCreated |
2010-8-3
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| pubmed:abstractText |
Schizophrenia is characterized by impaired visual contrast sensitivity and anomalous perceptual experiences. The aim of this study was to investigate these phenomena in unmedicated patients with first-episode schizophrenia. Visual contrast sensitivity was measured with pulsed-pedestal and steady-pedestal tests, which bias information processing toward the parvocellular and magnocellular pathways, respectively. Anomalous perceptual experiences were investigated with the Structured Interview for Assessing Perceptual Anomalies (SIAPA). Results revealed that patients with schizophrenia (n = 20) exhibited increased contrast sensitivity values on the magnocellular test relative to the control participants (n = 20). In the parvocellular condition, there was no significant difference between the two groups. The higher magnocellular contrast sensitivity values were associated with increased visual SIAPA scores, especially at the two lowest spatial frequencies (0.25 and 0.5 cycles/degree). These results indicate the heightened sensitivity of magnocellular pathways in unmedicated first-episode schizophrenia, which may contribute to anomalous perceptual experiences and sensory overloading.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:status |
MEDLINE
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| pubmed:month |
Aug
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| pubmed:issn |
1939-1846
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| pubmed:author | |
| pubmed:copyrightInfo |
Copyright 2010 APA, all rights reserved
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| pubmed:issnType |
Electronic
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| pubmed:volume |
119
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
586-93
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| pubmed:meshHeading |
pubmed-meshheading:20677847-Adult,
pubmed-meshheading:20677847-Case-Control Studies,
pubmed-meshheading:20677847-Contrast Sensitivity,
pubmed-meshheading:20677847-Female,
pubmed-meshheading:20677847-Humans,
pubmed-meshheading:20677847-Male,
pubmed-meshheading:20677847-Psychiatric Status Rating Scales,
pubmed-meshheading:20677847-Schizophrenia,
pubmed-meshheading:20677847-Schizophrenic Psychology,
pubmed-meshheading:20677847-Young Adult
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| pubmed:year |
2010
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| pubmed:articleTitle |
When doors of perception open: visual contrast sensitivity in never-medicated, first-episode schizophrenia.
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| pubmed:affiliation |
National Psychiatric Center, Semmelweis University, Balassa u. 6, 1083, Budapest, Hungary.
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| pubmed:publicationType |
Journal Article
|