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rdf:type |
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lifeskim:mentions |
umls-concept:C0005117,
umls-concept:C0021368,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0086982,
umls-concept:C0227651,
umls-concept:C0331858,
umls-concept:C0599946,
umls-concept:C1314939,
umls-concept:C1704640,
umls-concept:C1706515
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pubmed:issue |
1
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pubmed:dateCreated |
2010-11-15
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pubmed:abstractText |
Our previous studies demonstrated that berberine could improve the renal function in rats and mice with diabetic nephropathy (DN) and inhibit extracellular matrix (ECM) component, fibronectin (FN) expression in rat mesangial cells (MCs) cultured under high glucose. However, the molecular mechanisms have not been fully elucidated.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1872-8057
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
331
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
34-40
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pubmed:meshHeading |
pubmed-meshheading:20674665-Animals,
pubmed-meshheading:20674665-Berberine,
pubmed-meshheading:20674665-Cell Nucleus,
pubmed-meshheading:20674665-Cell Proliferation,
pubmed-meshheading:20674665-Extracellular Matrix,
pubmed-meshheading:20674665-Fibronectins,
pubmed-meshheading:20674665-Fluorescent Antibody Technique,
pubmed-meshheading:20674665-I-kappa B Proteins,
pubmed-meshheading:20674665-Inflammation,
pubmed-meshheading:20674665-Intercellular Adhesion Molecule-1,
pubmed-meshheading:20674665-Lipopolysaccharides,
pubmed-meshheading:20674665-Mesangial Cells,
pubmed-meshheading:20674665-Mice,
pubmed-meshheading:20674665-NF-kappa B,
pubmed-meshheading:20674665-Nitric Oxide Synthase Type II,
pubmed-meshheading:20674665-Protein Processing, Post-Translational,
pubmed-meshheading:20674665-Protein Transport,
pubmed-meshheading:20674665-Rats,
pubmed-meshheading:20674665-Rats, Sprague-Dawley,
pubmed-meshheading:20674665-Signal Transduction,
pubmed-meshheading:20674665-Transcription Factor RelA,
pubmed-meshheading:20674665-Transforming Growth Factor beta1
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pubmed:year |
2011
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pubmed:articleTitle |
Berberine attenuates lipopolysaccharide-induced extracelluar matrix accumulation and inflammation in rat mesangial cells: involvement of NF-?B signaling pathway.
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pubmed:affiliation |
School of Pharmaceutical Sciences, Sun Yat-Sen University, Guagnzhou 510006, Guangdong, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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