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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2010-9-6
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pubmed:abstractText |
Streptococcus gordonii is a pioneer colonizer of the enamel salivary pellicle that forms biofilm on the tooth surfaces. Recent reports show the surface protein analogue peptide {400 (T) of SspB 390-402 is substituted to K forming SspB (390-T400K-402)} from S. gordonii interacts strongly with salivary receptors to cariogenic bacteria, Streptococcus mutans. To characterize the analogue peptide biological activities, we investigated its binding and inhibiting effects, and the role of its amino acid moities.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
D
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1879-1506
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2010 Elsevier Ltd. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
55
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
754-62
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pubmed:meshHeading |
pubmed-meshheading:20673869-Adhesins, Bacterial,
pubmed-meshheading:20673869-Amino Acid Sequence,
pubmed-meshheading:20673869-Aspartic Acid,
pubmed-meshheading:20673869-Bacterial Adhesion,
pubmed-meshheading:20673869-Binding, Competitive,
pubmed-meshheading:20673869-Biofilms,
pubmed-meshheading:20673869-Biosensing Techniques,
pubmed-meshheading:20673869-Dental Pellicle,
pubmed-meshheading:20673869-Glutamic Acid,
pubmed-meshheading:20673869-Humans,
pubmed-meshheading:20673869-Lysine,
pubmed-meshheading:20673869-Peptides,
pubmed-meshheading:20673869-Protein Binding,
pubmed-meshheading:20673869-Protein Structure, Secondary,
pubmed-meshheading:20673869-Salivary Proteins and Peptides,
pubmed-meshheading:20673869-Streptococcus gordonii,
pubmed-meshheading:20673869-Streptococcus mutans
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pubmed:year |
2010
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pubmed:articleTitle |
Inhibition of Streptococcus mutans adherence and biofilm formation using analogues of the SspB peptide.
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pubmed:affiliation |
Department of Oral Health, Technology and Epidemiology, Graduate School of Dental Science, Kyusyu University, Fukuoka, 113-8549, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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