|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
3
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|
pubmed:dateCreated |
2011-3-14
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|
pubmed:abstractText |
Gemcitabine based regimens have been widely used in patients with advanced cholangiocarcinoma (CC), but no standard therapy exists. In this study we aimed to find the maximally tolerated dose (MTD) of a two-week schedule of fixed dose rate (FDR) gemcitabine (G), oxaliplatin (O) and capecitabine (C), and evaluate the safety and efficacy of this regimen in patients with advanced cholangiocarcinoma (CC).
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
Apr
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|
pubmed:issn |
1651-226X
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|
pubmed:author |
|
|
pubmed:issnType |
Electronic
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pubmed:volume |
50
|
|
pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
448-54
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pubmed:meshHeading |
pubmed-meshheading:20670085-Adult,
pubmed-meshheading:20670085-Aged,
pubmed-meshheading:20670085-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:20670085-Bile Duct Neoplasms,
pubmed-meshheading:20670085-Bile Ducts, Intrahepatic,
pubmed-meshheading:20670085-Cholangiocarcinoma,
pubmed-meshheading:20670085-Deoxycytidine,
pubmed-meshheading:20670085-Disease Progression,
pubmed-meshheading:20670085-Dose-Response Relationship, Drug,
pubmed-meshheading:20670085-Drug Administration Schedule,
pubmed-meshheading:20670085-Female,
pubmed-meshheading:20670085-Fluorouracil,
pubmed-meshheading:20670085-Humans,
pubmed-meshheading:20670085-Male,
pubmed-meshheading:20670085-Maximum Tolerated Dose,
pubmed-meshheading:20670085-Middle Aged,
pubmed-meshheading:20670085-Organoplatinum Compounds,
pubmed-meshheading:20670085-Treatment Outcome
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|
pubmed:year |
2011
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|
pubmed:articleTitle |
A Phase I-II dose escalation study of fixed-dose rate gemcitabine, oxaliplatin and capecitabine every two weeks in advanced cholangiocarcinomas.
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pubmed:affiliation |
Department of Oncology, The Finsen Centre, Rigshospitalet, Copenhagen, Denmark. ulrik.lassen@rh.regionh.dk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Multicenter Study,
Clinical Trial, Phase II,
Clinical Trial, Phase I
|
