Linked Life Data

20665291

Source:http://linkedlifedata.com/resource/pubmed/id/20665291

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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2010-7-28
pubmed:abstractText
The objective of this study was to use single nucleotide polymorphisms (SNP) located on bovine chromosome 20 to fine map a previously identified QTL associated with the incidence of infectious bovine keratoconjunctivitis (IBK). Crossbred steers (GPE 7; n = 539) derived from sires of 7 Bos taurus breeds and having veterinary records related to IBK were used to test the association of a total of 105 SNP located under the most relevant region of the QTL. Five SNP were significantly associated with IBK (P < 0.05), as animals inheriting differing genotypes from individual SNP exhibited significantly different incidence rates of IBK. The population also had numerous other phenotypes, supporting evaluation of association of the 105 markers with carcass traits to identify potential antagonistic effects of implementing a marker-assisted selection program for IBK susceptibility. An association of 2 SNP for marbling and tenderness was identified, along with 3 SNP associated with the percentage of carcasses classified as choice. Four SNP were significantly associated with fat yield, 2 SNP with longissimus muscle area, and 2 additional SNP with dressing percentage. The association of these markers indicates that the evaluated QTL region may, in fact, harbor the causative mutations responsible for the variation observed in IBK susceptibility and carcass quality and composition traits. Thus, further evaluation of SNP in this region is necessary in order to identify mutations accounting for the largest degree of variation for IBK and carcass traits.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1532-2378
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
188-202
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Markers on bovine chromosome 20 associated with carcass quality and composition traits and incidence of contracting infectious bovine keratoconjunctivitis.
pubmed:affiliation
USDA, ARS, U.S. Meat Animal Research Center, Clay Center, Nebraska 68933, USA.
pubmed:publicationType
Journal Article