Source:http://linkedlifedata.com/resource/pubmed/id/20663111
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2011-1-11
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pubmed:abstractText |
Amotosalen plus ultraviolet A (UVA) light inactivates a broad range of bacteria, viruses, protozoa, and leukocytes in platelet (PLT) and plasma components. Upon UVA illumination a small fraction of amotosalen reacts with the nucleic acid of contaminating pathogens and residual white blood cells and the remaining fraction undergoes photodegradation into defined photoproducts. The levels of amotosalen and photoproducts can be accurately quantified.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1537-2995
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pubmed:author | |
pubmed:copyrightInfo |
© 2010 American Association of Blood Banks.
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pubmed:issnType |
Electronic
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pubmed:volume |
51
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
52-61
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pubmed:meshHeading |
pubmed-meshheading:20663111-Blood Platelets,
pubmed-meshheading:20663111-Erythrocytes,
pubmed-meshheading:20663111-Humans,
pubmed-meshheading:20663111-Klebsiella pneumoniae,
pubmed-meshheading:20663111-Photolysis,
pubmed-meshheading:20663111-Psoralens,
pubmed-meshheading:20663111-Stem Cells,
pubmed-meshheading:20663111-Ultraviolet Rays
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pubmed:year |
2011
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pubmed:articleTitle |
The extent of amotosalen photodegradation during photochemical treatment of platelet components correlates with the level of pathogen inactivation.
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pubmed:affiliation |
Cerus Corp., Concord, California 94520, USA. wliu@cerus.com
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pubmed:publicationType |
Journal Article
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