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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2010-10-14
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pubmed:abstractText |
Culture medium for mesenchymal stromal cells (MSC) is frequently supplemented with fetal calf serum (FCS). FCS can induce xenogeneic immune reactions, transmit bovine pathogens and has a high lot-to-lot variability that hampers reproducibility of results. Several studies have demonstrated that pooled human platelet lysate (HPL) provides an attractive alternative for FCS. However, little is known about the variation between different platelet lysates.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1477-2566
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pubmed:author |
pubmed-author:BokermannGudrunG,
pubmed-author:BorkSimoneS,
pubmed-author:CholewaDominikD,
pubmed-author:DrescherWolfW,
pubmed-author:HoAnthony DAD,
pubmed-author:HornPatrickP,
pubmed-author:HutschenreutherGabrieleG,
pubmed-author:KochCarmenC,
pubmed-author:WagnerWolfgangW,
pubmed-author:WalendaThomasT,
pubmed-author:ZenkeMartinM
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pubmed:issnType |
Electronic
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
888-98
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pubmed:meshHeading |
pubmed-meshheading:20662607-Adipogenesis,
pubmed-meshheading:20662607-Animals,
pubmed-meshheading:20662607-Blood Platelets,
pubmed-meshheading:20662607-Cattle,
pubmed-meshheading:20662607-Cell Extracts,
pubmed-meshheading:20662607-Cell Proliferation,
pubmed-meshheading:20662607-Cell Separation,
pubmed-meshheading:20662607-Cells, Cultured,
pubmed-meshheading:20662607-Colony-Forming Units Assay,
pubmed-meshheading:20662607-Culture Media, Serum-Free,
pubmed-meshheading:20662607-Feasibility Studies,
pubmed-meshheading:20662607-Humans,
pubmed-meshheading:20662607-Immunophenotyping,
pubmed-meshheading:20662607-Mesenchymal Stem Cells,
pubmed-meshheading:20662607-Osteogenesis,
pubmed-meshheading:20662607-Platelet-Derived Growth Factor,
pubmed-meshheading:20662607-Serum
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pubmed:year |
2010
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pubmed:articleTitle |
Impact of individual platelet lysates on isolation and growth of human mesenchymal stromal cells.
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pubmed:affiliation |
Department of Medicine V, University of Heidelberg, Heidelberg, Germany.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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