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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
15
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pubmed:dateCreated |
2010-10-7
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pubmed:abstractText |
Long-QT syndromes are heritable diseases associated with prolongation of the QT interval on an electrocardiogram and a high risk of sudden cardiac death due to ventricular tachyarrhythmia. In long-QT syndrome type 1, mutations occur in the KCNQ1 gene, which encodes the repolarizing potassium channel mediating the delayed rectifier I(Ks) current.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1533-4406
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pubmed:author |
pubmed-author:BellinMilenaM,
pubmed-author:Bott-FlügelLorenzL,
pubmed-author:DornTatjanaT,
pubmed-author:GoedelAlexanderA,
pubmed-author:HöhnkeChristianC,
pubmed-author:HofmannFranzF,
pubmed-author:JungChristian BillyCB,
pubmed-author:LamJason TJT,
pubmed-author:LaugwitzKarl-LudwigKL,
pubmed-author:MorettiAlessandraA,
pubmed-author:SchömigAlbertA,
pubmed-author:SeyfarthMelchiorM,
pubmed-author:SinneckerDanielD,
pubmed-author:WellingAndreaA
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pubmed:issnType |
Electronic
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pubmed:day |
7
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pubmed:volume |
363
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1397-409
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pubmed:dateRevised |
2011-3-3
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pubmed:meshHeading |
pubmed-meshheading:20660394-Action Potentials,
pubmed-meshheading:20660394-Adrenergic beta-Antagonists,
pubmed-meshheading:20660394-Adult,
pubmed-meshheading:20660394-Aged,
pubmed-meshheading:20660394-Cardiotonic Agents,
pubmed-meshheading:20660394-Child,
pubmed-meshheading:20660394-Female,
pubmed-meshheading:20660394-Fibroblasts,
pubmed-meshheading:20660394-Gene Expression,
pubmed-meshheading:20660394-Humans,
pubmed-meshheading:20660394-Induced Pluripotent Stem Cells,
pubmed-meshheading:20660394-Isoproterenol,
pubmed-meshheading:20660394-KCNQ1 Potassium Channel,
pubmed-meshheading:20660394-Male,
pubmed-meshheading:20660394-Mutation, Missense,
pubmed-meshheading:20660394-Myocytes, Cardiac,
pubmed-meshheading:20660394-Pedigree,
pubmed-meshheading:20660394-Phenotype,
pubmed-meshheading:20660394-Potassium Channel Blockers,
pubmed-meshheading:20660394-Potassium Channels,
pubmed-meshheading:20660394-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:20660394-Romano-Ward Syndrome
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pubmed:year |
2010
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pubmed:articleTitle |
Patient-specific induced pluripotent stem-cell models for long-QT syndrome.
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pubmed:affiliation |
Cardiology Division, First Department of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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