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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2010-10-7
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pubmed:abstractText |
We have reported that growth differentiation factor 9 (GDF9) can enhance activin A (?(A)?(A))-induced inhibin B (??(B)) secretion in human granulosa-lutein (hGL) cells, but its effects on steroidogenic acute regulatory protein (StAR), ovarian steroidogenic enzymes, and progesterone production are unknown. We undertook this study to further evaluate GDF9 in this regard.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1945-7197
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
95
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
E172-80
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pubmed:meshHeading |
pubmed-meshheading:20660033-Activins,
pubmed-meshheading:20660033-Cells, Cultured,
pubmed-meshheading:20660033-Down-Regulation,
pubmed-meshheading:20660033-Drug Antagonism,
pubmed-meshheading:20660033-Female,
pubmed-meshheading:20660033-Gene Expression Regulation,
pubmed-meshheading:20660033-Growth Differentiation Factor 9,
pubmed-meshheading:20660033-Humans,
pubmed-meshheading:20660033-Inhibins,
pubmed-meshheading:20660033-Luteal Cells,
pubmed-meshheading:20660033-Phosphoproteins,
pubmed-meshheading:20660033-Progesterone,
pubmed-meshheading:20660033-RNA, Small Interfering,
pubmed-meshheading:20660033-Transfection
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pubmed:year |
2010
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pubmed:articleTitle |
Growth differentiation factor 9 reverses activin A suppression of steroidogenic acute regulatory protein expression and progesterone production in human granulosa-lutein cells.
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pubmed:affiliation |
Department of Obstetrics and Gynaecology, Child and Family Research Institute, University of British Columbia, Vancouver, British Columbia, Canada.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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