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pubmed:abstractText |
Twenty pigs were randomly divided into four groups of five pigs each (not transported - control, 1, 2 and 4h of transportation). A significant increase of ALT, AST and CK in the blood serum and acute parenchyma cell lesions were observed and those were characterized by acute degenerations in the heart and liver. Hsp27 expression levels increased significantly in the heart after 2h and in the liver after 4h of transportation, accompanying with the hsp27 mRNA increasing significantly in the heart and liver after 1h of transportation. ?B-crystallin expression levels were fluctuant (not significantly) in the heart and liver during transporting, however, ?B-crystallin mRNA increase notably in the heart after 1h and decrease significantly in the liver at 1 and 2h of transportation, respectively. In conclusion, the cellular damage to the heart and liver is highest after 1h of transportation, Hsp27 and ?B-crystallin play dissimilar roles and show tissue-specific response in different tissues during transportation.
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