Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2011-2-2
pubmed:abstractText
A second haemolytic crisis of blackwater fever (BWF) following a combination of artemether-lumefantrine intake, in an 8-year-old Congolese boy is reported. The patient had a history of BWF after quinine intake. He was given artemether-lumefantrine treatment for malaria. He was free from G6PD deficiency and abnormal haemoglobin. Sepsis was eliminated. Haemolysis was noted with 5.6 g/dl of haemoglobin, negative direct antiglobulin test, and LDH at 893 IU/l. Low-level Plasmodium falciparum was found. The outcome was favourable with rehydration. BWF has been described with quinine, mefloquine and halofantrine. Several case reports have been published of haemolysis after lumefantrine, but it is quite rare. This case has a major therapeutic implication: aryl-amino-alcohol should be strictly contraindicated in patients with history of BWF with aryl-amino-alcohols intake.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0037-9085
pubmed:author
pubmed:issnType
Print
pubmed:volume
103
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
296-8
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
[Haemolytic crisis of blackwater fever following artemether-lumefantrine intake].
pubmed:affiliation
Unité de Néphrologie Pédiatrique, Département de Pédiatrie, Cliniques Universitaires de Kinshasa, BP 123, Kinshasa-XI, République Démocratique du Congo. nephropedcuk@yahoo.fr
pubmed:publicationType
Journal Article, English Abstract, Case Reports