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pubmed-article:20657645pubmed:abstractTextLacking suitable alternatives, the control of malaria increasingly depends upon Artemisinin Combination Treatments (ACT): resistance to these drugs would therefore be disastrous. For ACTs, the biology of resistance to the individual components has been investigated, but experimentally induced resistance to component drugs in combination has not been generated.lld:pubmed
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pubmed-article:20657645pubmed:articleTitleExperimental evolution of resistance to artemisinin combination therapy results in amplification of the mdr1 gene in a rodent malaria parasite.lld:pubmed
pubmed-article:20657645pubmed:affiliationUEI Biologia Molecular, UEI Malária, Centro de Malária e Outras Doenças Tropicais/IHMT/UNL, Lisbon, Portugal.lld:pubmed
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