20657645

Source:http://linkedlifedata.com/resource/pubmed/id/20657645

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0009429, umls-concept:C0015219, umls-concept:C0024530, umls-concept:C0035804, umls-concept:C0052430, umls-concept:C0521066, umls-concept:C0556895, umls-concept:C0683598, umls-concept:C1274040, umls-concept:C1517004, umls-concept:C1521871, umls-concept:C1704939
pubmed:issue	7
pubmed:dateCreated	2010-7-26
pubmed:abstractText	Lacking suitable alternatives, the control of malaria increasingly depends upon Artemisinin Combination Treatments (ACT): resistance to these drugs would therefore be disastrous. For ACTs, the biology of resistance to the individual components has been investigated, but experimentally induced resistance to component drugs in combination has not been generated.
pubmed:commentsCorrections	http://linkedlifedata.com/resource/pubmed/commentcorrection/20657645-10365399, http://linkedlifedata.com/resource/pubmed/commentcorrection/20657645-10582887, http://linkedlifedata.com/resource/pubmed/commentcorrection/20657645-11323308, http://linkedlifedata.com/resource/pubmed/commentcorrection/20657645-11485094, http://linkedlifedata.com/resource/pubmed/commentcorrection/20657645-11846609, http://linkedlifedata.com/resource/pubmed/commentcorrection/20657645-12121922, http://linkedlifedata.com/resource/pubmed/commentcorrection/20657645-12543682, http://linkedlifedata.com/resource/pubmed/commentcorrection/20657645-15138066, http://linkedlifedata.com/resource/pubmed/commentcorrection/20657645-15322230, http://linkedlifedata.com/resource/pubmed/commentcorrection/20657645-15679555, http://linkedlifedata.com/resource/pubmed/commentcorrection/20657645-15937493, http://linkedlifedata.com/resource/pubmed/commentcorrection/20657645-16436700, http://linkedlifedata.com/resource/pubmed/commentcorrection/20657645-16518375, http://linkedlifedata.com/resource/pubmed/commentcorrection/20657645-17124182, http://linkedlifedata.com/resource/pubmed/commentcorrection/20657645-17152017, http://linkedlifedata.com/resource/pubmed/commentcorrection/20657645-17581118, http://linkedlifedata.com/resource/pubmed/commentcorrection/20657645-1820703, http://linkedlifedata.com/resource/pubmed/commentcorrection/20657645-19234601, http://linkedlifedata.com/resource/pubmed/commentcorrection/20657645-19641219, http://linkedlifedata.com/resource/pubmed/commentcorrection/20657645-19883322, http://linkedlifedata.com/resource/pubmed/commentcorrection/20657645-7015505, http://linkedlifedata.com/resource/pubmed/commentcorrection/20657645-7985758, http://linkedlifedata.com/resource/pubmed/commentcorrection/20657645-8302844, http://linkedlifedata.com/resource/pubmed/commentcorrection/20657645-8426608, http://linkedlifedata.com/resource/pubmed/commentcorrection/20657645-9463672
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/101285081
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Antimalarials, http://linkedlifedata.com/resource/pubmed/chemical/Artemisinins, http://linkedlifedata.com/resource/pubmed/chemical/Mefloquine, http://linkedlifedata.com/resource/pubmed/chemical/Multidrug Resistance-Associated..., http://linkedlifedata.com/resource/pubmed/chemical/Protozoan Proteins
pubmed:status	MEDLINE
pubmed:issn	1932-6203
pubmed:author	pubmed-author:BorgesSofia TST, pubmed-author:CravoPedroP, pubmed-author:HenriquesGiselaG, pubmed-author:HuntPaulP, pubmed-author:MartinelliAxelA, pubmed-author:RodriguesLouise ALA, pubmed-author:SanchezCecília PCP
pubmed:issnType	Electronic
pubmed:volume	5
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	e11593
pubmed:meshHeading	pubmed-meshheading:20657645-Animals, pubmed-meshheading:20657645-Antimalarials, pubmed-meshheading:20657645-Artemisinins, pubmed-meshheading:20657645-Blotting, Western, pubmed-meshheading:20657645-Drug Resistance, pubmed-meshheading:20657645-Malaria, pubmed-meshheading:20657645-Mefloquine, pubmed-meshheading:20657645-Mice, pubmed-meshheading:20657645-Multidrug Resistance-Associated Proteins, pubmed-meshheading:20657645-Plasmodium chabaudi, pubmed-meshheading:20657645-Polymerase Chain Reaction, pubmed-meshheading:20657645-Protozoan Proteins, pubmed-meshheading:20657645-Sequence Analysis, DNA
pubmed:year	2010
pubmed:articleTitle	Experimental evolution of resistance to artemisinin combination therapy results in amplification of the mdr1 gene in a rodent malaria parasite.
pubmed:affiliation	UEI Biologia Molecular, UEI Malária, Centro de Malária e Outras Doenças Tropicais/IHMT/UNL, Lisbon, Portugal.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't